Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL4795442 | 0.92 | PTGS1 (0.40) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL4795100 | 0.88 | PTGS1 (0.40) | PTGS1PTGS2XDHHIF1ASKP2 | |
| SCHEMBL4799147 | 0.81 | ALDH1A1 (0.46) | XDHHIF1AEPAS1CYP3A4TSHR | |
| SCHEMBL4799196 | 0.81 | PTGS1 (0.38) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL4800628 | 0.77 | PTGS1 (0.53) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL14930314 | 0.75 | PTGS1 (0.54) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| Carbamic Acid SCHEMBL4800912 | 0.74 | ALDH1A1 (0.50) | XDHHIF1AEPAS1CYP3A4ALDH1A1 | |
| SCHEMBL14178686 | 0.70 | MEN1 (0.41) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL2558890 | 0.69 | PTGS1 (0.46) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL2562052 | 0.69 | XDH (0.50) | PTGS1PTGS2XDHHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | ALOX5, LOX, ALOX15 | PTGS1 36/4885PTGS2 31/4885XDH 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.