Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686655 | 0.82 | CA1 (0.67) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL16653533 | 0.82 | CA1 (0.67) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL480132 | 0.80 | ENPP2 (0.67) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL20595738 | 0.78 | CA1 (0.61) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL5665675 | 0.78 | CA1 (0.61) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL28050158 | 0.78 | NQO1 (0.54) | PRSS1PRSS2PRSS3LTA4HTDP1 | |
| SCHEMBL27965000 | 0.77 | CA2 (0.54) | CA1CA2ENPP2ACHECES2 | |
| SCHEMBL5710098 | 0.77 | CA1 (0.73) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL4673 | 0.77 | CA2 (1.00) | CA1CA2ENPP2CA7CA9 | |
| SCHEMBL184420 | 0.77 | TRPV6 (0.50) | CA1CA2ENPP2CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330642-A | Selenophen compound | INOR WUHAN PHARMACEUTICAL CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-103864750-A | Derivative of N-biphenyl dichloroacetamide as well as preparation method and applications thereof | UNIV TSINGHUA | 2014-06-18 | — | — | CN | claimed |
| CN-106573927-B | Oxyclohepten-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | 豪夫迈·罗氏有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110248929-A | Benzylamino pyrazinyl cyclopropane-carboxylic acid, its pharmaceutical composition and purposes | 勃林格殷格翰国际有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109803660-A | Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphoma | 细胞基因公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105272967-B | Triazines epidermal growth factor receptor inhibitor and its application | 南京圣和药业股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109790357-A | Curable modified petroleum resin, preparation method and the usage | 可隆工业株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-109641996-A | Curable petroleum resin, process for its preparation and its use | 可隆工业株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-109476599-A | Guanidine derivatives and its medical usage | 东丽株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-106632004-B | Pyridinone derivatives and the preparation method and application thereof | 山东大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-102448954-A | Substituted quinazolines as fungicides | SYNGENTA PARTICIPATIONS AG | 2012-05-09 | — | — | CN | disclosed |
| WO-2011029802-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| US-20110059961-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. | 2011-03-10 | — | — | US | disclosed |
| CN-101094848-A | Organic compounds | NOVARTIS AG (CH) | 2007-12-26 | — | — | CN | disclosed |
| CN-1279026-C | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2006-10-11 | — | — | CN | disclosed |
| CN-1738788-A | Substituted phenylnaphthalenes as estrogenic agents | WYETH CORP (US) | 2006-02-22 | — | — | CN | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1342149-A | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059961-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | PIM1, PIM3, PIM2 | CA1 4599/4885CA2 2380/4885ENPP2 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.