Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 11/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012004 | 0.91 | HIF1A (0.46) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL8066269 | 0.78 | COXFA4 (0.53) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL30874660 | 0.78 | COXFA4 (0.53) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| Carbamic Acid SCHEMBL4800108 | 0.78 | PTGS1 (0.44) | COXFA4HIF1AEPAS1XDHPTGS1 | |
| Carbamic Acid SCHEMBL4800912 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL3193312 | 0.77 | ODC1 (0.47) | ALDH1A1HPGDCYP3A4TDP1HIF1A | |
| SCHEMBL27666053 | 0.77 | HIF1A (0.54) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL6648245 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL9685221 | 0.75 | CA12 (0.56) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL2825117 | 0.75 | HIF1A (0.52) | ALDH1A1HPGDCYP3A4TDP1COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | ALOX5, LOX, ALOX15 | ALDH1A1 1656/4885HPGD 401/4885CYP3A4 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.