Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805173 | 0.96 | HDAC1 (0.53) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4801474 | 0.95 | HDAC1 (0.55) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4808274 | 0.84 | HTT (0.55) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4812192 | 0.82 | LMNA (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4807419 | 0.79 | HDAC1 (0.49) | KMT2AALDH1A1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL4807423 | 0.79 | HDAC1 (0.51) | KMT2AALDH1A1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL13754013 | 0.78 | KDM4E (0.51) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4812181 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10630917 | 0.74 | LMNA (0.75) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11621538 | 0.74 | MAPT (0.81) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427260-B2 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20040096904-A1 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-05-20 | — | — | US | disclosed |
| WO-2002079278-A1 | EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |