Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807419 | 0.86 | HDAC1 (0.49) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL13754013 | 0.86 | KDM4E (0.51) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL4812192 | 0.85 | LMNA (0.51) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL4807423 | 0.81 | HDAC1 (0.51) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7849684 | 0.81 | ALDH1A1 (0.59) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30912248 | 0.78 | ALDH1A1 (0.77) | ALDH1A1POLBKDM4ELMNAALOX15 | |
| SCHEMBL614963 | 0.78 | ALDH1A1 (0.77) | ALDH1A1POLBKDM4ELMNAALOX15 | |
| SCHEMBL4801436 | 0.77 | MAPT (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2HDAC1 | |
| SCHEMBL4808274 | 0.76 | HTT (0.55) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL4805173 | 0.76 | HDAC1 (0.53) | ALDH1A1LMNASMN1; SMN2HDAC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427260-B2 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20040096904-A1 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-05-20 | — | — | US | disclosed |
| WO-2002079278-A1 | EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |