Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812192 | 0.91 | LMNA (0.51) | HDAC1HDAC3LMNASMN1; SMN2POLB | |
| SCHEMBL4807419 | 0.88 | HDAC1 (0.49) | HDAC1HDAC3LMNASMN1; SMN2POLB | |
| SCHEMBL4808274 | 0.85 | HTT (0.55) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL4805173 | 0.84 | HDAC1 (0.53) | HDAC1HDAC3LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4801474 | 0.83 | HDAC1 (0.55) | HDAC1HDAC3LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13754013 | 0.83 | KDM4E (0.51) | HDAC1LMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4812181 | 0.81 | ALDH1A1 (0.49) | HDAC1HDAC3LMNASMN1; SMN2POLB | |
| SCHEMBL4801436 | 0.79 | MAPT (0.50) | HDAC1HDAC3LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30843288 | 0.79 | HTT (0.65) | HDAC1HDAC3SMN1; SMN2POLBHPGD | |
| SCHEMBL8515238 | 0.76 | ALDH1A1 (0.57) | HDAC1HDAC3LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427260-B2 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20040096904-A1 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-05-20 | — | — | US | disclosed |
| WO-2002079278-A1 | EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |