Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL886984 | 0.78 | ALOX15 (0.33) | MAPTOPRM1OPRD1SIGMAR1MEN1 | |
| SCHEMBL10708711 | 0.78 | MAPT (0.43) | MAPTOPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL14306942 | 0.75 | — | — | |
| SCHEMBL4801538 | 0.75 | ALDH1A1 (0.43) | ALDH1A1DHFRHTR2CTSHROPRM1 | |
| SCHEMBL3388230 | 0.71 | NPC1 (0.39) | ALDH1A1MAPTDHFRTSHR | |
| SCHEMBL13006966 | 0.71 | NPC1 (0.39) | ALDH1A1MAPTDHFRTSHR | |
| SCHEMBL5062027 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTDHFRHTR2CTSHR | |
| SCHEMBL6284322 | 0.71 | CTSL (0.38) | ALDH1A1MAPTOPRM1 | |
| SCHEMBL6284323 | 0.71 | CTSL (0.36) | MAPTPOLBOPRM1 | |
| SCHEMBL7070471 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402639-B2 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-07-22 | — | — | US | disclosed |
| US-6927295-B2 | A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (SE) | 2005-06-16 | — | — | US | disclosed |
| US-6683142-B2 | PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-27 | — | — | US | disclosed |
| US-20030220423-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (CH) | 2003-11-27 | — | — | US | disclosed |
| US-20020107397-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6353107-B1 | FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | PYM1, PTGER1, CBR1 | ALDH1A1 638/4885MAPT 4633/4885DHFR 3068/4885 |
| US-20020107397-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | CBR1, PYM1, ELOC | ALDH1A1 508/4885MAPT 4391/4885DHFR 2683/4885 |
| US-20030220423-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | PYM1, ELOC, CBR1 | ALDH1A1 666/4885MAPT 4497/4885DHFR 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.