SCHEMBL4801581

SCHEMBL4801581

CCCCCCCCCCCC(=O)OC1CC(C)(C)N([O])C(CC)(CC)C1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.51
DGKA P23743 1/20 0.37
PRKCA P17252 6/20 0.37
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
PAM P19021 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4799930 1.00 NAAA (0.51) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL4801583 0.87 NAAA (0.51) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL4799937 0.87 NAAA (0.51) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL728303 0.84 NAAA (0.47) NAAAPRKCASMN1; SMN2
SCHEMBL1138472 0.83 NAAA (0.47) NAAADGKAPRKCA
SCHEMBL316828 0.82 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL17296568 0.82 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL15299923 0.82 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL5198548 0.82 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL2221561 0.82 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 US claimed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 US claimed
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2003-09-04 US claimed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US claimed
US-7402639-B2 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SPECIALTY CHEMICALS CORP. (US) 2008-07-22 US disclosed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 US disclosed
US-6927295-B2 A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-08-09 US disclosed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 US disclosed
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (SE) 2005-06-16 US disclosed
US-6891008-B2 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-10 US disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 US disclosed
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2003-09-04 US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed
US-6353107-B1 FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 NAAA 1401/4885DGKA 1204/4885PRKCA 2986/4885
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, PTGER1, CBR1 NAAA 2099/4885DGKA 1941/4885PRKCA 2066/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC NAAA 2741/4885DGKA 1398/4885PRKCA 1947/4885
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 NAAA 1401/4885DGKA 1204/4885PRKCA 2986/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 NAAA 1401/4885DGKA 1204/4885PRKCA 2986/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 NAAA 2977/4885DGKA 1451/4885PRKCA 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.