Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.40 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985358 | 0.84 | AADAT (0.56) | AADATPOLBALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6532282 | 0.78 | CYP3A4 (0.39) | AADATLMNAPYGLGOT1KYAT1 | |
| SCHEMBL4802349 | 0.77 | NPY1R (0.45) | CA12CA1CA2CA9POLB | |
| SCHEMBL650180 | 0.77 | ALDH1A1 (0.53) | AADATCA1CA2POLBALDH1A1 | |
| SCHEMBL650181 | 0.77 | ALDH1A1 (0.53) | AADATCA1CA2POLBALDH1A1 | |
| SCHEMBL5134148 | 0.77 | ALDH1A1 (0.53) | AADATCA1CA2POLBALDH1A1 | |
| SCHEMBL4870896 | 0.76 | AADAT (0.43) | AADATALDH1A1MEN1KMT2AADORA2A | |
| SCHEMBL4797980 | 0.75 | PYGL (0.47) | POLBALDH1A1PYGLGAA | |
| SCHEMBL5179725 | 0.74 | ALDH1A1 (0.60) | POLBALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL22426223 | 0.74 | ALDH1A1 (0.60) | POLBALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-20060154956-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154956-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | CNR1, CNR2, CCKBR | AADAT 2393/4885CA12 3578/4885CA1 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.