Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | BMP1 | P13497 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609210 | 0.94 | CALM1 (0.60) | CALM1IDO1TAAR1MMP8MMP13 | |
| SCHEMBL1255034 | 0.86 | IDO1 (0.67) | CALM1IDO1TAAR1MAOBSIGMAR1 | |
| SCHEMBL244070 | 0.86 | CALM1 (0.79) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL4254058 | 0.86 | CALM1 (0.72) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL17400406 | 0.84 | CALM1 (0.69) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL10571532 | 0.84 | CALM1 (0.69) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL11007798 | 0.84 | CALM1 (0.69) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL9509173 | 0.84 | CALM1 (0.69) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL5609056 | 0.83 | CALM1 (0.62) | CALM1IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL834551 | 0.81 | TAAR1 (0.73) | CALM1IDO1TAAR1MAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230124527-A1 | NANOPARTICLES FOR CHEMIRESISTOR SENSORS | NANOSCENT LTD. (IL) | 2023-04-20 | — | — | US | disclosed |
| EP-3094680-B1 | INTERIOR TRAIN COMPONENTS HAVING LOW SMOKE AND LOW HEAT RELEASE, AND METHODS OF THEIR MANUFACTURE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2018-05-16 | — | — | EP | disclosed |
| US-7410995-B1 | N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders | GPI NIL HOLDINGS INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
| US-6943187-B2 | Pyrrolidine derivative hair growth compositions and uses | GPI NIL HOLDINGS, INC. (US) | 2005-09-13 | — | — | US | disclosed |
| EP-1479373-A1 | Hair growth compositions and uses | GPI NIL Holdings, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040186098-A1 | Method for preventing and treating hearing loss using sensorineurotrophic compounds | AMGEN INC. | 2004-09-23 | — | — | US | disclosed |
| WO-2000009107-A2 | SULFONAMIDES OF N-CONTAINING HETEROCYCLIC THIOESTERS FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009108-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| US-6004993-A | TREATMENT OF ALOPECIA IN ANIMALS | GPI NIL HOLDINGS, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1999062489-A1 | N-LINKED SULFONAMIDE OF HETEROCYCLIC THIOESTER HAIR GROWTH COMPOUNDS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0957913-A1 | N-LINKED SULFONAMIDES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| US-5874449-A | INHIBITORS OF IMMUNOPHILIN | GPI NIL HOLDINGS, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1998055090-A1 | HAIR GROWTH COMPOSITIONS AND USES | GUILFORD PHARMACEUTICALS INC. (US) | 1998-12-10 | — | — | WO | disclosed |
| WO-1998029116-A1 | N-LINKED SULFONAMIDES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186098-A1 | Method for preventing and treating hearing loss using sensorineurotrophic compounds | GAP43, CHAT, MYOC | CALM1 4065/4885IDO1 1729/4885TAAR1 895/4885 |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | CALM1 1156/4885IDO1 4195/4885TAAR1 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.