SCHEMBL4803

SCHEMBL4803

Brc1ccnc(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 3/20 0.59
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
GABRA1 P14867 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
NLRP3 Q96P20 1/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MIF P14174 1/20 0.44
AURKA O14965 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PRKACA P17612 1/20 0.44
ADORA2A P29274 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.43
HTR1A P08908 1/20 0.42
HTR7 P34969 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31645963 1.00 ASIC3 (0.59) ASIC3NPC1RAB9AGABRA1GABRG2
SCHEMBL19614420 0.86 GABRA1 (0.45) ASIC3NPC1RAB9AGABRA1GABRG2
SCHEMBL1925061 0.85 IDO1 (0.50) ASIC3NPC1RAB9AGABRA1GABRG2
SCHEMBL16210551 0.84 MEN1 (0.47) ASIC3NPC1RAB9ANLRP3KDM4E
SCHEMBL28580746 0.84 ASIC3 (0.43) ASIC3NPC1RAB9AGABRA1GABRG2
SCHEMBL26129711 0.84 MEN1 (0.50) ASIC3KDM4EALDH1A1SMN1; SMN2ADORA2A
SCHEMBL31191934 0.84 MEN1 (0.50) ASIC3KDM4EALDH1A1SMN1; SMN2ADORA2A
SCHEMBL26127676 0.83 MEN1 (0.44) ASIC3NPC1RAB9AKDM4EALDH1A1
SCHEMBL5760081 0.83 SMN1; SMN2 (0.44) ASIC3NPC1RAB9AKDM4EALDH1A1
SCHEMBL833371 0.81 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2GRM5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
CN-113004194-B Circular polarization luminescent organic micro-nano crystal material and preparation method and application thereof 中国科学院化学研究所 2022-12-09 CN claimed
CN-113004191-B White circular polarization luminescent organic micro-nano crystal material and preparation method thereof 中国科学院化学研究所 2022-08-05 CN claimed
CN-110818834-B Room-temperature phosphorescent material based on polymer hydrogen bonds and preparation method thereof 南开大学 2021-06-29 CN claimed
CN-113004191-A White circular polarization luminescent organic micro-nano crystal material and preparation method thereof 中国科学院化学研究所 2021-06-22 CN claimed
CN-113004194-A Circular polarization luminescent organic micro-nano crystal material and preparation method and application thereof 中国科学院化学研究所 2021-06-22 CN claimed
CN-110818834-A Room-temperature phosphorescent material based on polymer hydrogen bonds and preparation method thereof 南开大学 2020-02-21 CN claimed
CN-104059630-B A kind of novel red phosphorescence material and synthetic method thereof 宁波大学 2016-06-15 CN claimed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4658650-A1 HETEROCYCLIC COMPOUNDS Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250353846-A1 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2025-11-20 US disclosed
WO-2025215558-A1 COMPOUNDS FOR SPLICING MODULATION FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-10-16 WO disclosed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO disclosed
WO-2007005404-A1 AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION WYETH (US) 2007-01-11 WO disclosed
WO-2007005404-A1 AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION WYETH (US) 2007-01-11 WO disclosed
US-20070004730-A1 Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation WYETH (US) 2007-01-04 US disclosed
US-20070004730-A1 Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation WYETH (US) 2007-01-04 US disclosed
US-20070004730-A1 Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation WYETH (US) 2007-01-04 US disclosed
CN-1772838-A Electroluminescent material of dendritic functional Ir (III) metal organic complex UNIV XI AN JIAOTONG (CN) 2006-05-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004730-A1 Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation BACE1, BACE2, APP ASIC3 4086/4885NPC1 293/4885RAB9A 1731/4885
US-20260125378-A2 Heterocyclic Compounds NFATC1, CD4, MALT1 ASIC3 4696/4885NPC1 978/4885RAB9A 1314/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 ASIC3 1755/4885NPC1 1159/4885RAB9A 1211/4885
US-20250353846-A1 Heterocyclic Compounds NFATC1, CD4, ACIN1 ASIC3 4829/4885NPC1 1729/4885RAB9A 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.