SCHEMBL480603

SCHEMBL480603

CC(C)C(=O)c1ccc(Cc2ccc(C(=O)C(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
GAA P10253 2/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 1/20 0.50
DBH P09172 1/20 0.50
RECQL P46063 1/20 0.50
SRD5A2 P31213 2/20 0.46
PLA2G10 O15496 1/20 0.45
PLA2G2A P14555 1/20 0.45
HDAC1 Q13547 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
PLK1 P53350 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2C19 P33261 1/20 0.41
PTGS2 P35354 1/20 0.41
TSHR P16473 1/20 0.40
CHRM2 P08172 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418831 0.92 LMNA (0.63) KMT2AGAALMNAKDM4EDBH
SCHEMBL3685675 0.86 KDM4E (0.50) KMT2AGAALMNAKDM4EDBH
SCHEMBL21812139 0.86 KMT2A (0.44) KMT2AGAALMNAKDM4EDBH
SCHEMBL480572 0.86 GAA (0.47) KMT2AGAALMNAKDM4EDBH
SCHEMBL10121174 0.85 KDM4E (0.62) KMT2AGAALMNAKDM4EDBH
SCHEMBL3129690 0.84 ALDH1A1 (0.59) GAALMNAKDM4EDBHRECQL
SCHEMBL12158530 0.84 SLC6A2 (0.49) KMT2AGAAKDM4EDBHRECQL
SCHEMBL28533988 0.84 TSHR (0.50) KMT2AGAALMNAKDM4EDBH
SCHEMBL12674312 0.84 KMT2A (0.47) KMT2AGAALMNAKDM4EDBH
SCHEMBL7495940 0.83 KDM4E (0.47) KMT2AGAAKDM4EDBHRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1442005-B1 NOVEL DIFUNCTIONAL PHOTOINITIATORS CIBA HOLDING INC (CH) 2009-03-18 EP claimed
US-7084183-B2 Difunctional photoinitiators CIBA SPECIALTY CHEMCIALS CORP. (US) 2006-08-01 US claimed
US-20050004249-A1 Novel disfunctional photoinitiators IGM GROUP B.V. (NL) 2005-01-06 US claimed
EP-1442005-A2 NOVEL DIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2004-08-04 EP claimed
WO-2003040076-A2 NOVEL DIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-15 WO claimed
CN-112442292-A Active energy ray-curable antiglare hard coating agent, cured film, and laminated film 荒川化学工业株式会社 2021-03-05 CN disclosed
EP-2411359-B1 NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2017-02-01 EP disclosed
US-8604251-B2 Oligofunctional photoinitiators BASF SE (DE) 2013-12-10 US disclosed
US-20120029107-A1 NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2012-02-02 US disclosed
EP-2411359-A1 NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2012-02-01 EP disclosed
WO-2010108862-A1 NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2010-09-30 WO disclosed
EP-1620475-B1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2009-11-11 EP disclosed
EP-1620475-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2006-02-01 EP disclosed
EP-1613706-A1 RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR Ciba SC Holding AG (CH) 2006-01-11 EP disclosed
US-20050004249-A1 Novel disfunctional photoinitiators IGM GROUP B.V. (NL) 2005-01-06 US disclosed
WO-2004099262-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed
WO-2004092287-A1 RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-10-28 WO disclosed
EP-1442005-A2 NOVEL DIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2004-08-04 EP disclosed
WO-2003040076-A2 NOVEL DIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-15 WO disclosed
US-4374984-A Aromatic-aliphatic ketones useful as photoinitiators MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029107-A1 NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS CCNA1, CCNT1, TET1 KMT2A 530/4885GAA 4404/4885LMNA 4153/4885
US-20050004249-A1 Novel disfunctional photoinitiators ETFA, ETFB, PAH KMT2A 889/4885GAA 1112/4885LMNA 2221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.