Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453640 | 0.79 | ALDH1A1 (0.44) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL28182200 | 0.77 | GLRA3 (0.41) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL1278621 | 0.76 | GLRA3 (0.46) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL10769690 | 0.76 | GLRA3 (0.46) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL410919 | 0.74 | GLRA3 (0.42) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL28429448 | 0.74 | VCAM1 (0.44) | GLRA3GLRBGPR55 | |
| SCHEMBL1277895 | 0.73 | ALOX15 (0.48) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL10413968 | 0.72 | GLRA3 (0.38) | GLRA3GLRBALDH1A1ALOX15LMNA | |
| SCHEMBL7792915 | 0.72 | FFAR1 (0.45) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL7792669 | 0.71 | CYP3A4 (0.54) | GLRA3GLRBALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339003-B2 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20050145831-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | ALDRICH HAVEN S (US) | 2005-07-07 | — | — | US | disclosed |
| US-6689724-B2 | HIGH NUMBER OF HYDROXYL POLYOL ESTERS ANTIOXIDANTS WHEN GRAFTED ONTO MINERAL OILS, POLYOL ESTERS, POLYALPHA OLEFIN BASE STOCKS, FUELS, OLIGOMERS AND POLYMERS CAN INCREASE THE OXIDATION STABILITY; LUBRICANTS; OIL ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2004-02-10 | — | — | US | disclosed |
| WO-2002092734-A1 | ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020082174-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | EXXONMOBIL RESEARCH & ENGINEERING CO. | 2002-06-27 | — | — | US | disclosed |
| EP-0590360-B1 | Process for the preparation of aryl-substituted propionic acid esters | MONTELL NORTH AMERICA INC (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0590360-A2 | Process for the preparation of aryl-substituted propionic acid esters | MONTELL NORTH AMERICA INC. (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5264612-A | Process for the preparation of aryl-substituted propionic acid esters | HIMONT INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082174-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | GPX4, LPO, CAT | GLRA3 1951/4885GLRB 1769/4885ALDH1A1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.