Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28009564 | 1.00 | — | — | |
| Water SCHEMBL1720535 | 1.00 | — | — | |
| Water SCHEMBL9007676 | 1.00 | — | — | |
| Water SCHEMBL28369663 | 0.87 | — | — | |
| Water SCHEMBL21145587 | 0.87 | — | — | |
| Water SCHEMBL28371945 | 0.87 | — | — | |
| Water SCHEMBL2722910 | 0.87 | — | — | |
| Water SCHEMBL22408509 | 0.87 | — | — | |
| Water SCHEMBL11587171 | 0.87 | — | — | |
| Water SCHEMBL28165720 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080220090-A1 | selectively exploit chemical variations between normal cells and cancer cells to inhibit or prevent the proliferation of cancerous cells; biologically acceptable copper compound | SABIN ROBERT | 2008-09-11 | — | — | US | claimed |
| US-20080014150-A1 | Compositions and method for treating precancerous virus infection and prevention of cancer | SABIN ROBERT | 2008-01-17 | — | — | US | claimed |
| US-20060147512-A1 | Compositions and methods of use for treatment of mammalian diseases | SABIN ROBERT | 2006-07-06 | — | — | US | claimed |
| WO-2006017179-A1 | COMPOSITIONS AND METHODS OF USE FOR TREATMENT OF MAMMALIAN DISEASES | SABIN ROBERT (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060008535-A1 | Anti tumor compositions and methods of use | SABIN ROBERT | 2006-01-12 | — | — | US | claimed |
| EP-1614414-A2 | Compositions comprising a copper compound for treatment of mammalian diseases | Sabin, Robert (US) | 2006-01-11 | — | — | EP | claimed |
| US-10328030-B2 | Compositions and methods of use for treatment of mammalian diseases | SABIN ROBERT (US) | 2019-06-25 | — | — | US | disclosed |
| US-10004234-B2 | Potentiation of fixed coppers and other pesticides containing copper and supplementing plant nutrition | SABIN ROBERT (US) | 2018-06-26 | — | — | US | disclosed |
| US-9854807-B2 | Potentiation of fixed coppers and other pesticides containing copper and supplementing plant nutrition | SABIN ROBERT (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170339962-A1 | POTENTIATION OF FIXED COPPERS AND OTHER PESTICIDES CONTAINING COPPER AND SUPPLEMENTING PLANT NUTRITION | SABIN ROBERT (US) | 2017-11-30 | — | — | US | disclosed |
| WO-2017131958-A1 | POTENTIATION OF FIXED COPPERS AND OTHER PESTICIDES | SABIN ROBERT (US) | 2017-08-03 | — | — | WO | disclosed |
| US-9718739-B2 | Potentiation of fixed coppers and other pesticides containing copper and supplementing plant nutrition | SABIN ROBERT (US) | 2017-08-01 | — | — | US | disclosed |
| US-9717251-B2 | Potentiation of fixed coppers and other pesticides containing copper and supplementing plant nutrition | SABIN ROBERT (US) | 2017-08-01 | — | — | US | disclosed |
| US-7449196-B2 | Anti tumor compositions and methods of use | SABIN ROBERT | 2008-11-11 | — | — | US | disclosed |
| US-20080220090-A1 | selectively exploit chemical variations between normal cells and cancer cells to inhibit or prevent the proliferation of cancerous cells; biologically acceptable copper compound | SABIN ROBERT | 2008-09-11 | — | — | US | disclosed |
| US-20080081051-A1 | Method of manufacturing anti-tumor and anti-viral compositions | Sabin, Robert | 2008-04-03 | — | — | US | disclosed |
| US-20080014150-A1 | Compositions and method for treating precancerous virus infection and prevention of cancer | SABIN ROBERT | 2008-01-17 | — | — | US | disclosed |
| US-20060147512-A1 | Compositions and methods of use for treatment of mammalian diseases | SABIN ROBERT | 2006-07-06 | — | — | US | disclosed |
| WO-2006017179-A1 | COMPOSITIONS AND METHODS OF USE FOR TREATMENT OF MAMMALIAN DISEASES | SABIN ROBERT (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060008535-A1 | Anti tumor compositions and methods of use | SABIN ROBERT | 2006-01-12 | — | — | US | disclosed |