Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Putrescine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 3/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL8214090 | 0.97 | DNM1 (0.50) | CA5ACA5BNFKB1LMNABLM | |
| Nitric Acid SCHEMBL6736968 | 0.97 | DNM1 (0.50) | CA5ACA5BNFKB1LMNABLM | |
| Nitric Acid SCHEMBL10620356 | 0.93 | — | — | |
| Nitric Acid SCHEMBL10940709 | 0.89 | CA5A (0.42) | CA5ACA5BNFKB1LMNABLM | |
| Nitric Acid SCHEMBL28345264 | 0.87 | DNM1 (0.57) | CA5ACA5BTSHRDNM1KMT2A | |
| Ethylenediamine SCHEMBL723589 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL28858090 | 0.86 | CA5A (0.61) | CA5ACA5BLMNABLMTSHR | |
| Ethylenediamine SCHEMBL721753 | 0.86 | CA5A (0.61) | CA5ACA5BLMNABLMTSHR | |
| Ethylenediamine SCHEMBL6232364 | 0.86 | CA5A (0.61) | CA5ACA5BLMNABLMTSHR | |
| Ethylenediamine SCHEMBL2733332 | 0.86 | CA5A (0.61) | CA5ACA5BLMNABLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034073-A | Explosive composition with binder | AEROJET GENERAL CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-7431083-B2 | Sub-surface coalbed methane well enhancement through rapid oxidation | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-20070240880-A1 | Sub-Surface Coalbed Methane Well Enhancement Through Rapid Oxidation | SCHLUMBERGER TECHNOLOGY CORPORATION | 2007-10-18 | — | — | US | disclosed |
| EP-1845233-A1 | Sub-surface coalbed methane well enhancement through rapid oxidation | Services Pétroliers Schlumberger (FR) | 2007-10-17 | — | — | EP | disclosed |
| US-5034073-A | Explosive composition with binder | AEROJET GENERAL CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |