Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438712 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL4012822 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL15027430 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL10081536 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL517696 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL31540500 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL27039953 | 0.83 | USP2 (0.53) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL10081314 | 0.80 | USP2 (0.50) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7296270 | 0.78 | MAPT (0.41) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7290348 | 0.78 | MAPT (0.41) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371779-B2 | Synergistic compositions of N-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) | 2008-05-13 | — | — | US | claimed |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | THE UNIVERSITY OF NOTTINGHAM (GB) | 2005-01-20 | — | — | US | claimed |
| US-20040259942-A1 | Modulation of stat activity | SHAW PETER (GB) | 2004-12-23 | — | — | US | claimed |
| EP-1404315-B1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | UNIV NOTTINGHAM (GB) | 2004-11-03 | — | — | EP | claimed |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2004-10-07 | — | — | US | claimed |
| EP-1427406-A2 | MODULATION OF STAT ACTIVITY | University of Nottingham (GB) | 2004-06-16 | — | — | EP | claimed |
| EP-1425274-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2004-06-09 | — | — | EP | claimed |
| EP-1404315-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2004-04-07 | — | — | EP | claimed |
| US-20030171371-A1 | Immunosuppressant n-acyles homoserine lactones | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-09-11 | — | — | US | claimed |
| WO-2003026641-A2 | MODULATION OF STAT ACTIVITY | UNIVERSITY OF NOTTINGHAM (GB) | 2003-04-03 | — | — | WO | claimed |
| WO-2003022828-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-03-20 | — | — | WO | claimed |
| WO-2003004017-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-16 | — | — | WO | claimed |
| EP-1268459-A1 | IMMUNOSUPPRESSANT N-ACYL HOMOSERINE LACTONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-02 | — | — | EP | claimed |
| WO-2001074801-A1 | IMMUNOSUPPRESSANT N-ACYLES HOMOSERINE LACTONES | UNIVERSITY OF NOTTINGHAM (GB) | 2001-10-11 | — | — | WO | claimed |
| US-7371779-B2 | Synergistic compositions of N-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) | 2008-05-13 | — | — | US | disclosed |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | THE UNIVERSITY OF NOTTINGHAM (GB) | 2005-01-20 | — | — | US | disclosed |
| US-20040259942-A1 | Modulation of stat activity | SHAW PETER (GB) | 2004-12-23 | — | — | US | disclosed |
| WO-2003026641-A2 | MODULATION OF STAT ACTIVITY | UNIVERSITY OF NOTTINGHAM (GB) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003022828-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003004017-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259942-A1 | Modulation of stat activity | STAT3, STAT1, STAT4 | ALDH1A1 3710/4885USP2 2223/4885MAPT 4800/4885 |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | HPGDS, CD14, IFNG | ALDH1A1 3938/4885USP2 729/4885MAPT 4663/4885 |
| US-20030171371-A1 | Immunosuppressant n-acyles homoserine lactones | MSR1, IL4, SRR | ALDH1A1 3041/4885USP2 2784/4885MAPT 4833/4885 |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | CBR3, CBR1, CNR1 | ALDH1A1 2586/4885USP2 3982/4885MAPT 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.