Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779040 | 0.88 | L3MBTL1 (0.37) | TSHRCA2MPOKDM4ERECQL | |
| SCHEMBL314763 | 0.85 | TSHR (0.40) | TSHRCA2MPO | |
| SCHEMBL757705 | 0.83 | PTPN1 (0.37) | KDM4E | |
| SCHEMBL8672408 | 0.81 | LTA4H (0.43) | TSHRKDM4ERECQL | |
| SCHEMBL6132567 | 0.80 | KCNA3 (0.35) | TSHRKDM4E | |
| SCHEMBL1143957 | 0.80 | SMN1; SMN2 (0.38) | TSHRKDM4E | |
| SCHEMBL2499529 | 0.80 | LTA4H (0.34) | — | |
| SCHEMBL7283060 | 0.80 | LTA4H (0.44) | TSHRRECQL | |
| SCHEMBL6132896 | 0.79 | KDM4E (0.35) | KDM4E | |
| SCHEMBL9031404 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181082-B | Synthetic method of natural molecule Moracin M | 江苏集萃分子工程研究院有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-115181082-A | Synthetic method of natural molecule Moracin M | 江苏集萃分子工程研究院有限公司 | 2022-10-14 | — | — | CN | disclosed |
| US-7338941-B2 | Pharmaceutical compositions for lowering blood glucose and blood cholesterol levels | DIAKRON PHARMACEUTICALS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1501520-A1 | PHARMACEUTICAL COMPOSITIONS FOR LOWERING BLOOD GLUCOSE AND BLOOD CHOLESTEROL LEVELS | Diakron Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040006128-A1 | Pharmaceutical compositions for lowering blood glucose and blood cholesterol levels | Knobbe, Martens, Olson & Bear, LLP | 2004-01-08 | — | — | US | disclosed |
| WO-2003094928-A1 | PHARMACEUTICAL COMPOSITIONS FOR LOWERING BLOOD GLUCOSE AND BLOOD CHOLESTEROL LEVELS | DIAKRON PHARMACEUTICALS, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| EP-0693496-A1 | Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1996-01-24 | — | — | EP | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006128-A1 | Pharmaceutical compositions for lowering blood glucose and blood cholesterol levels | APOB, HDLBP, SERPINA6 | TSHR 4369/4885CA2 2732/4885MPO 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.