Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132896 | 0.98 | KDM4E (0.35) | KCNA3KDM4EMEN1KMT2ALMNA | |
| SCHEMBL1143957 | 0.96 | SMN1; SMN2 (0.38) | KCNA3KDM4EMEN1KMT2ALMNA | |
| SCHEMBL314763 | 0.90 | TSHR (0.40) | SMN1; SMN2TSHR | |
| SCHEMBL7779040 | 0.85 | L3MBTL1 (0.37) | KDM4EMEN1KMT2ALMNANPC1 | |
| SCHEMBL167283 | 0.85 | LTA4H (0.46) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6238419 | 0.83 | JAK2 (0.33) | KCNA3KDM4ELMNAGAAALDH1A1 | |
| SCHEMBL5495328 | 0.83 | LTA4H (0.44) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4943659 | 0.83 | LTA4H (0.44) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL338315 | 0.83 | LTA4H (0.44) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL659359 | 0.83 | LTA4H (0.44) | KDM4EMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | claimed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | claimed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | claimed |
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |
| US-4584376-A | 1-heterocyclicthio-1-cyclopropanecarbonitriles as crop protectants | MONSANTO COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4272278-A | 1-Methyl-2-aryl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxides, herbicidal compositions and the use thereof | MONSANTO COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4250320-A | Process for producing substituted benzoxaphospholes | MONSANTO COMPANY (US) | 1981-02-10 | — | — | US | disclosed |