Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202888 | 0.89 | MAPT (0.53) | MAPTLMNAALOX15HSD17B10HTT | |
| SCHEMBL9047865 | 0.81 | MEN1 (0.62) | MAPTALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL2576239 | 0.81 | IGF1R (0.47) | MAPTALOX15SMN1; SMN2SLC5A1HSP90AA1 | |
| SCHEMBL364672 | 0.81 | ESR1 (0.53) | MAPTTRPA1LMNAALOX15HSD17B10 | |
| SCHEMBL1616373 | 0.80 | HIF1A (0.54) | MAPTLMNAALOX15HSD17B10HTT | |
| SCHEMBL4809365 | 0.80 | AMY1A (0.59) | MAPTTRPA1ALOX15HSD17B10KDM4E | |
| SCHEMBL3869091 | 0.79 | LMNA (0.43) | MAPTLMNAALOX15HSD17B10KDM4E | |
| SCHEMBL6202554 | 0.79 | AMY1A (0.58) | MAPTTRPA1ALOX15HSD17B10MEN1 | |
| SCHEMBL48207 | 0.79 | MEN1 (0.69) | MAPTTRPA1LMNAALOX15HSD17B10 | |
| SCHEMBL4813970 | 0.79 | ALDH1A1 (0.61) | MAPTTRPA1LMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414072-B2 | Aryl 5-thio-β-d-glucopyranoside derivatives and therapeutic agents for diabetes containing the same | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-19 | — | — | US | disclosed |
| CN-100341885-C | Process for selective production of aryl 5-thio-beta-d-aldohexopyranosides | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-10-10 | — | — | CN | disclosed |
| US-7250522-B2 | Method for selective preparation of aryl 5-thio-β-D-aldohexopyranosides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| CN-1312165-C | Aryl 5-thio-beta-D-glucopyranoside derivative and therapeutic agent for diabetes containing the same | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-04-25 | — | — | CN | disclosed |
| US-20050256317-A1 | Process for selective production of aryl 5-thio-beta-d- aldohexopyranosides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| CN-1675233-A | Process for selective production of aryl 5-thio-beta-d-aldohexopyranosides | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-20050209309-A1 | Aryl 5-thio-beta-d-glucopyranoside derivatives and remedies for diabetes containing the same | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-22 | — | — | US | disclosed |
| CN-1639180-A | Aryl 5-thio-beta-D-glucopyranoside derivatives and remedies for diabetes containing the same | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| EP-1541578-A1 | PROCESS FOR SELECTIVE PRODUCTION OF ARYL 5-THIO-BETA-D-ALDOHEXOPYRANOSIDES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1528066-A1 | ARYL 5-THIO-D-GLUCOPYRANOSIDE DERIVATIVES AND REMEDIES FOR DIABETES CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256317-A1 | Process for selective production of aryl 5-thio-beta-d- aldohexopyranosides | ALDOA, DERA, AKR1D1 | MAPT 4518/4885TRPA1 3804/4885LMNA 4746/4885 |
| US-20050209309-A1 | Aryl 5-thio-beta-d-glucopyranoside derivatives and remedies for diabetes containing the same | SLC5A2, SLC5A1, UGGT1 | MAPT 885/4885TRPA1 719/4885LMNA 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.