SCHEMBL4814962

SCHEMBL4814962

[c]1c(-c2ccccc2)cc(-c2ccccc2)c2c1Cc1c(-c3ccccc3)ccc(-c3ccccc3)c1-2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.33
PARP11 Q9NR21 1/20 0.33
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4821609 0.75
SCHEMBL4822531 0.70 PARP10 (0.31) PARP10PARP11
SCHEMBL1029672 0.68 PARP10 (0.35) PARP10PARP11
SCHEMBL8530924 0.67 BACE1 (0.37) ALOX5
SCHEMBL3443207 0.66 ADORA2A (0.38)
SCHEMBL28376546 0.64 ADORA2A (0.49) PARP10PARP11
SCHEMBL717055 0.60 TDP2 (0.46) PARP10PARP11
SCHEMBL23087114 0.60 KDR (0.39)
SCHEMBL216860 0.60 ALDH1A1 (0.38)
SCHEMBL10622407 0.60 PARP10 (0.45) PARP10PARP11ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337536-B1 CATIONIC GROUP-3 CATALYST SYSTEM EXXONMOBIL CHEM PATENTS INC (US) 2012-09-12 EP disclosed
US-7390861-B2 Cationic group-3 catalyst system EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-24 US disclosed
US-20040033891-A1 Cationic group-3 catalyst system EXXONMOBIL CHEMICAL PATENTS INC. 2004-02-19 US disclosed
EP-1337536-A1 CATIONIC GROUP-3 CATALYST SYSTEM ExxonMobil Chemical Patents Inc. (US) 2003-08-27 EP disclosed
WO-2002032909-A1 CATIONIC GROUP-3 CATALYST SYSTEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033891-A1 Cationic group-3 catalyst system COG3, ORC3, LIG3 PARP10 565/4885PARP11 1455/4885ALOX5 564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.