SCHEMBL4815058

SCHEMBL4815058

CON1C(C)(C)CC(OC(=O)c2ccc3nn(-c4cc(C(C)(C)CC(C)(C)C)cc(C(C)(C)c5ccccc5)c4O)nc3c2)CC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815065 0.90 CNR2 (0.35) TSHRKMT2AGAA
SCHEMBL5668737 0.85 ACSS2 (0.39) GAA
SCHEMBL5186823 0.81 ACSS2 (0.35) KMT2AGAA
SCHEMBL7147637 0.80 NPC1 (0.33)
SCHEMBL4814951 0.77 TSHR (0.31) TSHR
SCHEMBL76991 0.77 NPC1 (0.40)
SCHEMBL29353178 0.77 NPC1 (0.40)
SCHEMBL22080467 0.76 SHBG (0.36)
SCHEMBL5648042 0.75 NPC1 (0.34)
SCHEMBL7787049 0.75 NPC1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US claimed
WO-2002079173-A1 BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
US-7419513-B2 Hindered amine light stabilizers (HALS); for thermoset/thermoplastic resins, photographic applications, pigmented/dyed polypropylene, polyamide/polyester fibers, and for white, dyed, dipped, unscented/scented candle wax against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-02 US disclosed
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith WOOD MERVIN G (US) 2005-02-24 US disclosed
US-6846929-B2 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-01-25 US disclosed
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US disclosed
WO-2002079173-A1 BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith TAS1R1, TAS1R2, BRWD1 TSHR 1693/4885KMT2A 416/4885GAA 751/4885
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith BRWD1, TAS1R2, TAS1R1 TSHR 1196/4885KMT2A 402/4885GAA 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.