SCHEMBL4815065

SCHEMBL4815065

CCCCCC(C)(C)c1cc(-n2nc3ccc(C(=O)OC4CC(C)(C)N(OC)C(C)(C)C4)cc3n2)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.35
CNR1 P21554 5/20 0.35
TSHR P16473 2/20 0.35
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815058 0.90 TSHR (0.37) TSHRKMT2AGAA
SCHEMBL5668740 0.86 CNR2 (0.41) CNR2CNR1
SCHEMBL7143518 0.83 CNR2 (0.39) CNR2CNR1KMT2A
SCHEMBL7147640 0.81 CNR1 (0.33) CNR2CNR1
SCHEMBL224924 0.78 CNR1 (0.38) CNR2CNR1
SCHEMBL10484223 0.78 CNR2 (0.37) CNR2CNR1
SCHEMBL5693443 0.77 CNR2 (0.34) CNR2CNR1KMT2A
SCHEMBL7787052 0.77 CNR1 (0.34) CNR2CNR1
SCHEMBL5648044 0.77 CNR2 (0.36) CNR2CNR1
SCHEMBL5648165 0.76 CNR2 (0.37) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US claimed
WO-2002079173-A1 BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
US-7419513-B2 Hindered amine light stabilizers (HALS); for thermoset/thermoplastic resins, photographic applications, pigmented/dyed polypropylene, polyamide/polyester fibers, and for white, dyed, dipped, unscented/scented candle wax against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-02 US disclosed
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith WOOD MERVIN G (US) 2005-02-24 US disclosed
US-6846929-B2 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-01-25 US disclosed
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US disclosed
WO-2002079173-A1 BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith TAS1R1, TAS1R2, BRWD1 CNR2 2287/4885CNR1 2693/4885TSHR 1693/4885
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith BRWD1, TAS1R2, TAS1R1 CNR2 2138/4885CNR1 2706/4885TSHR 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.