Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451557 | 0.79 | TSHR (0.47) | TDP1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10538992 | 0.79 | TSHR (0.47) | TDP1TSHRMAPTMEN1KMT2A | |
| SCHEMBL11151271 | 0.78 | TDP1 (0.60) | TDP1L3MBTL1TSHRCES2CES1 | |
| SCHEMBL11755785 | 0.78 | TSHR (0.49) | TDP1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10649978 | 0.77 | MAPK1 (0.46) | TDP1L3MBTL1TSHRMAPK1MAPT | |
| SCHEMBL10652013 | 0.77 | VCAM1 (0.47) | TDP1L3MBTL1TSHRMAPTNPC1 | |
| SCHEMBL2257980 | 0.77 | TDP1 (0.64) | TDP1L3MBTL1TSHRCES2CES1 | |
| SCHEMBL3824611 | 0.77 | TDP1 (0.64) | TDP1L3MBTL1TSHRCES2CES1 | |
| SCHEMBL7318386 | 0.77 | ALDH1A1 (0.41) | TDP1L3MBTL1TSHRMAPTLMNA | |
| SCHEMBL10653026 | 0.76 | TDP1 (0.45) | TDP1L3MBTL1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414011-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (US) | 2008-08-19 | — | — | US | disclosed |
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | CBR3, CBR1, CYC1 | TDP1 4471/4885L3MBTL1 807/4885TSHR 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.