Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | PRKCA | P17252 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.62 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813459 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL5936405 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL4814107 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL5936352 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL5944372 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL4812404 | 0.99 | ALDH1A1 (0.70) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL5936406 | 0.94 | ALDH1A1 (0.72) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL6026492 | 0.93 | ALDH1A1 (0.59) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL14178795 | 0.93 | ALDH1A1 (0.59) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Tritetradecylthioacetyl Glycerol SCHEMBL4815254 | 0.93 | ALDH1A1 (0.59) | ALDH1A1LMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | claimed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | claimed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | claimed |
| US-7375135-B2 | Fatty acid derivatives; preparation and uses thereof | GENFIT (FR) | 2008-05-20 | — | — | US | disclosed |
| US-7375135-B2 | Fatty acid derivatives; preparation and uses thereof | GENFIT (FR) | 2008-05-20 | — | — | US | disclosed |
| EP-1673338-B1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-09-19 | — | — | EP | disclosed |
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | GENFIT (FR) | 2006-11-09 | — | — | US | disclosed |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | disclosed |
| EP-1673338-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | Genfit (FR) | 2006-06-28 | — | — | EP | disclosed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| EP-1587508-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | Genfit (FR) | 2005-10-26 | — | — | EP | disclosed |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | GENFIT (FR) | 2004-09-30 | — | — | US | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004069241-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | GENFIT (FR) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003014073-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | SGMS2, SGMS1, AGK | ALDH1A1 3402/4885LMNA 4519/4885PRKCA 2280/4885 |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | FASN, FFAR1, PLIN5 | ALDH1A1 1220/4885LMNA 239/4885PRKCA 574/4885 |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | AGPAT5, HAGH, AGPAT2 | ALDH1A1 1482/4885LMNA 4213/4885PRKCA 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.