Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 19/20 | 0.50 |
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817094 | 0.86 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL4818478 | 0.85 | PPARG (0.58) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL4815612 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL420670 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL2364446 | 0.76 | PPARG (0.69) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL3182619 | 0.76 | RXRA (0.53) | — | |
| SCHEMBL4820077 | 0.75 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL4820511 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL28669667 | 0.75 | PPARG (0.65) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8935664 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | SMN1; SMN2 4525/4885PPARG 570/4885PPARA 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.