Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627034 | 0.80 | USP2 (0.70) | MEN1KMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL15791191 | 0.78 | NPSR1 (0.67) | MEN1KMT2ANPSR1ALDH1A1GSK3A | |
| SCHEMBL21027095 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2ANPSR1ALDH1A1GSK3A | |
| SCHEMBL5087842 | 0.76 | MEN1 (0.55) | MEN1KMT2AP2RX4ALDH1A1 | |
| SCHEMBL11453331 | 0.76 | ALDH1A1 (0.77) | MEN1KMT2ANPSR1ALDH1A1GSK3A | |
| SCHEMBL12311071 | 0.75 | P2RX4 (0.59) | P2RX4 | |
| SCHEMBL5737827 | 0.75 | GAA (0.47) | MEN1KMT2ARXFP1NPSR1P2RX4 | |
| Iodide SCHEMBL8040227 | 0.74 | NPSR1 (0.48) | MEN1KMT2ANPSR1ALDH1A1GSK3A | |
| SCHEMBL5738618 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2ARXFP1P2RX4ALDH1A1 | |
| SCHEMBL4987320 | 0.73 | ALDH1A1 (0.71) | MEN1KMT2ANPSR1ALDH1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414128-B2 | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, LIMITED (IN) | 2008-08-19 | — | — | US | disclosed |
| US-7414128-B2 | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, LIMITED (IN) | 2008-08-19 | — | — | US | disclosed |
| US-7414128-B2 | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, LIMITED (IN) | 2008-08-19 | — | — | US | disclosed |
| US-20050159600-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, INC. | 2005-07-21 | — | — | US | disclosed |
| US-20030004341-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | EBDRUP SOREN (DK) | 2003-01-02 | — | — | US | disclosed |
| WO-2000063189-A1 | CRYSTALLINE R- GUANIDINES, ARGININE OR (L) -ARGININE (2S) -2- ETHOXY -3-{4- [2-(10H -PHENOXAZIN -10-YL)ETHOXY]PHENYL}PROPANOATE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159600-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | PRMT3, ARG1, ARGLU1 | MEN1 4456/4885KMT2A 3369/4885RXFP1 331/4885 |
| US-20030004341-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | PRMT3, ARG1, ARGLU1 | MEN1 4480/4885KMT2A 2788/4885RXFP1 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.