Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819129 | 0.72 | OGFRL1 (0.43) | MEN1KMT2ACNR1 | |
| SCHEMBL2992060 | 0.70 | FABP4 (0.34) | POLBUSP2KDM4EHSD17B10CNR2 | |
| SCHEMBL4291351 | 0.68 | OGFRL1 (0.44) | CNR1 | |
| SCHEMBL13211567 | 0.68 | GPR35 (0.32) | TP53MAPTALDH1A1LMNARAB9A | |
| SCHEMBL2990743 | 0.67 | SLC6A9 (0.33) | ALDH1A1LMNARAB9A | |
| SCHEMBL8823172 | 0.67 | KDM4E (0.50) | KDM4EHSD17B10MDM2KMT2ATP53 | |
| SCHEMBL2998826 | 0.66 | KDM4E (0.36) | POLBKDM4EMEN1KMT2ATP53 | |
| SCHEMBL4294427 | 0.65 | OGFRL1 (0.48) | MDM2MEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL4500497 | 0.64 | CNR2 (0.58) | POLBUSP2CNR2CNR1 | |
| SCHEMBL10017800 | 0.64 | EPHX1 (0.42) | POLBUSP2CNR2CNR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |