Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 13/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291351 | 0.80 | OGFRL1 (0.44) | OGFRL1OPRM1OPRK1OPRD1ADRB2 | |
| SCHEMBL4294427 | 0.78 | OGFRL1 (0.48) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL4284918 | 0.73 | OGFRL1 (0.53) | OGFRL1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL4281769 | 0.73 | OGFRL1 (0.53) | OGFRL1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL4819112 | 0.72 | POLB (0.46) | CNR1MEN1KMT2A | |
| SCHEMBL4285173 | 0.68 | ALDH1A1 (0.45) | OGFRL1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL4282795 | 0.68 | ALDH1A1 (0.45) | OGFRL1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL4293262 | 0.66 | SLC6A3 (0.43) | GAAALOX15CNR1MEN1KMT2A | |
| SCHEMBL3494784 | 0.65 | OGFRL1 (0.44) | OGFRL1OPRM1OPRK1GAAALOX15 | |
| SCHEMBL885809 | 0.64 | OPRM1 (0.47) | OGFRL1OPRM1OPRK1OPRD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |