Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976558 | 0.89 | L3MBTL1 (0.53) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL17432580 | 0.87 | L3MBTL1 (0.60) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL9135642 | 0.85 | KMT2A (0.55) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL4825168 | 0.84 | RAB9A (0.49) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL4825004 | 0.82 | L3MBTL1 (0.58) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL13681704 | 0.82 | MAPT (0.54) | L3MBTL1RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL12992039 | 0.82 | MAPT (0.54) | L3MBTL1RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL7221265 | 0.82 | KMT2A (0.58) | L3MBTL1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL18569607 | 0.81 | ALDH1A1 (0.47) | L3MBTL1RAB9AKDM4EALDH1A1RECQL | |
| SCHEMBL3792640 | 0.81 | ALDH1A1 (0.45) | L3MBTL1RAB9AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365064-B2 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-29 | — | — | US | disclosed |
| CN-1982299-A | Benzoxasine and benzothiasine derivatives and pharmaceutical composition containing the same | REDDY RES FOUNDATION (IN) | 2007-06-20 | — | — | CN | disclosed |
| US-20050113368-A1 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2005-05-26 | — | — | US | disclosed |
| CN-1596249-A | benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2005-03-16 | — | — | CN | disclosed |
| EP-1436268-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033481-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113368-A1 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | CYP3A5, HBZ, CYP4Z1 | L3MBTL1 4671/4885RAB9A 3400/4885KDM4E 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.