Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450084 | 0.90 | RAB9A (0.85) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL6751080 | 0.84 | NPC1 (0.68) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL600674 | 0.84 | ERCC5 (0.72) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL10488403 | 0.83 | LMNA (1.00) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL1904124 | 0.83 | MAPT (0.73) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL268855 | 0.83 | RAB9A (0.73) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL7090275 | 0.83 | NPC1 (1.00) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL1177177 | 0.82 | RAB9A (0.72) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL9395070 | 0.82 | POLB (0.72) | RAB9ANPC1MAPTPOLBLMNA | |
| SCHEMBL25706901 | 0.82 | RAB9A (0.67) | RAB9ANPC1MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345090-B2 | Galenical formulation | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345090-B2 | Galenical formulation | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345090-B2 | Galenical formulation | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |
| EP-1205475-B1 | Flavonoid compounds for use against oxidative stress and UV radiation | MERCK PATENT GMBH (DE) | 2004-10-27 | — | — | EP | disclosed |
| US-20040202624-A1 | Galenical formulation | PFLUECKER FRANK (DE) | 2004-10-14 | — | — | US | disclosed |
| US-20020106338-A1 | Galenical formulation | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-08-08 | — | — | US | disclosed |
| EP-1205475-A1 | Flavonoid compounds for use against oxidative stress and UV radiation | MERCK PATENT GmbH (DE) | 2002-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040202624-A1 | Galenical formulation | GALR1, GLA, GALR3 | RAB9A 2679/4885NPC1 3373/4885MAPT 2887/4885 |
| US-20020106338-A1 | Galenical formulation | GALR1, GLA, GALR3 | RAB9A 2679/4885NPC1 3373/4885MAPT 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.