SCHEMBL1904124

SCHEMBL1904124

CC(C)(C)c1ccc(C(=O)CC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.73
NPC1 O15118 2/20 0.73
RAB9A P51151 2/20 0.73
LMNA P02545 3/20 0.67
ALDH1A1 P00352 2/20 0.67
RECQL P46063 2/20 0.67
ALOX15 P16050 1/20 0.67
APEX1 P27695 1/20 0.67
MAPK1 P28482 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
TYR P14679 1/20 0.61
ESRRG P62508 7/20 0.61
ESRRB O95718 2/20 0.59
HTT P42858 1/20 0.59
KCNH2 Q12809 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HDAC1 Q13547 2/20 0.55
POLB P06746 1/20 0.53
DEGS1 O15121 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450084 0.92 RAB9A (0.85) MAPTNPC1RAB9ALMNAALDH1A1
Avobenzone SCHEMBL2526688 0.89 LMNA (0.88) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL7090275 0.85 NPC1 (1.00) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL268855 0.85 RAB9A (0.73) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL23093687 0.84 LMNA (0.63) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL1177177 0.84 RAB9A (0.72) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL3987484 0.83 NPC1 (0.65) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL13550744 0.83 RAB9A (0.71) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL4828018 0.83 RAB9A (0.71) MAPTNPC1RAB9ALMNAALDH1A1
SCHEMBL13550716 0.83 NPC1 (0.71) MAPTNPC1RAB9ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595936-B1 COMPOSITION FOR EXTERNAL USE VITAMIN C60 BIORES CORP (JP) 2011-10-19 EP claimed
US-20060134095-A1 Antioxidative composition and composition for external use VITAMIN C60 BIORESEARCH CORPORATION (JP) 2006-06-22 US claimed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP claimed
JP-2243647-A None JP disclosed
JP-6279666-A None JP disclosed
WO-2024090506-A1 HAIR IMPROVING AGENT AND HAIR IMPROVEMENT COMPOSITION リファインホールディングス株式会社 2024-05-02 WO disclosed
WO-2024057859-A1 OIL-IN-WATER TYPE COSMETIC 株式会社タイキ 2024-03-21 WO disclosed
US-20230285258-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2023-09-14 US disclosed
US-20230210755-A1 FUNCTIONAL SKIN COATING POLYMER THE JOHNS HOPKINS UNIVERSITY 2023-07-06 US disclosed
CN-114502132-A Near-infrared blocking agent and near-infrared blocking skin preparation for external use 东洋美妆株式会社 2022-05-13 CN disclosed
WO-2021046706-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2021-03-18 WO disclosed
US-20060134095-A1 Antioxidative composition and composition for external use VITAMIN C60 BIORESEARCH CORPORATION (JP) 2006-06-22 US disclosed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP disclosed
US-6914075-B2 Cystine derivative and agent for suppressing activation of inflammatory factors AJINOMOTO CO., INC. (JP) 2005-07-05 US disclosed
US-20040156802-A1 Cosmetics or external preparations for skin AJINOMOTO CO., INC. (JP) 2004-08-12 US disclosed
US-20040059110-A1 Novel cystine derivative and agent for suppressing activation of inflammatory factors AJINOMOTO CO., INC. (JP) 2004-03-25 US disclosed
EP-1374831-A1 COMSETICS OR EXTERNAL PREPARAIOTNS FOR SKIN Ajinomoto Co., Inc. (JP) 2004-01-02 EP disclosed
EP-1364943-A1 NOVEL CYSTINE DERIVATIVES AND INHIBITORS FOR THE ACTIVATION OF INFLAMMATORY FACTORS Ajinomoto Co., Inc. (JP) 2003-11-26 EP disclosed
JP-H06279666-A POLYCARBONATE RESIN COMPOSITION MITSUBISHI GAS CHEM CO INC 1994-10-04 JP disclosed
JP-H02243647-A 4-HYDROXYDIBENZOYLMETHANE DERIVATIVE, UV LIGHT ABSORBENT AND COSMETIC PIAS ARISE KK 1990-09-27 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210755-A1 FUNCTIONAL SKIN COATING POLYMER CUTA, PUF60, SUN2 MAPT 699/4885NPC1 3697/4885RAB9A 2816/4885
US-20040059110-A1 Novel cystine derivative and agent for suppressing activation of inflammatory factors CTH, CBS, CYSLTR1 MAPT 3925/4885NPC1 4296/4885RAB9A 3259/4885
US-20060134095-A1 Antioxidative composition and composition for external use GPX4, GPX1, SOD1 MAPT 3027/4885NPC1 1691/4885RAB9A 3841/4885
US-20040156802-A1 Cosmetics or external preparations for skin CUTA, PSAP, CTH MAPT 4196/4885NPC1 2806/4885RAB9A 3357/4885
US-20230285258-A1 A SUNSCREEN FORMULATION CUTA, NISCH, SUN2 MAPT 1336/4885NPC1 639/4885RAB9A 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.