Water

Water

SCHEMBL482851

CCCOCCC.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27726108 1.00 HSD17B10 (0.45)
Water SCHEMBL3140430 0.96 HSD17B10 (0.43)
Hydroxyl Radical SCHEMBL28108301 0.95
SCHEMBL23448 0.95
SCHEMBL28418615 0.95 HSD17B10 (0.47)
Ethylene SCHEMBL28204288 0.92 HSD17B10 (0.41)
Hydrochloric Acid SCHEMBL9464115 0.91
SCHEMBL17586846 0.91 HSD17B10 (0.45)
SCHEMBL1728920 0.91
SCHEMBL7799602 0.91 HSD17B10 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206947-A Curing method for microwave initiated curing 万果新材料科技(上海)有限公司 2024-06-18 CN claimed
CN-115894938-B Carbon hydroxyl organic silicon polyether copolymer, polyurethane resin and preparation method thereof 浙江华峰新材料有限公司 2024-02-02 CN claimed
CN-116904018-A High-performance laminated glass intermediate polymer film and preparation method thereof 长春工业大学 2023-10-20 CN claimed
CN-113956522-B Preparation method of high-strength polyurethane product 长春工业大学 2023-06-02 CN claimed
CN-114149560-B Wet polyurethane resin and preparation method and application thereof 福建汇得新材料有限公司 2023-05-05 CN claimed
CN-115894938-A Carbon hydroxyl organic silicon polyether copolymer, polyurethane resin and preparation method thereof 浙江华峰新材料有限公司 2023-04-04 CN claimed
WO-2022242167-A1 POLYURETHANE HAVING ANTI-ULTRAVIOLET PERFORMANCE AND PREPARATION METHOD THEREFOR 福建师范大学泉港石化研究院 2022-11-24 WO claimed
CN-113789588-A Degradable melt-spun polyurethane elastic fiber 华峰化学股份有限公司 2021-12-14 CN claimed
CN-110591158-B Modified core-shell type aluminum oxide and polyurethane composite material, and preparation method and application thereof 浙江华峰新材料有限公司 2021-10-08 CN claimed
CN-113214637-A Polyurethane with uvioresistant performance and preparation method thereof 福建师范大学泉港石化研究院 2021-08-06 CN claimed
CN-1640258-A Composition for killing harmful arthorpod with contact killing, stomach toxicity and ovicidal action SHENGNONG BIOLOG CHEMICAL PROD (CN) 2005-07-20 CN claimed
US-6875514-B2 Coating composition containing polytrimethylene ether diol useful as a primer composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-04-05 US claimed
WO-2005026268-A2 BRANCHED POLYMERS AND COATING COMPOSITIONS MADE THEREFROM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-03-24 WO claimed
US-20050054767-A1 Branched polymers and coating compositions made therefrom AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2005-03-10 US claimed
US-20040258923-A1 Coating composition containing polytrimethylene ether diol useful as a clear coat composition and as a primer composition AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2004-12-23 US claimed
US-20040249061-A1 Polytrimethylene ether diol containing coating compositions AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2004-12-09 US claimed
WO-2004085507-A1 COATING COMPOSITION CONTAINING POLYTRIMETHYLENE ETHER DIOL USEFUL AS A CLEAR COAT COMPOSITION AND AS A PRIMER COMPOSITION E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-10-07 WO claimed
WO-2004085558-A1 POLYTRIMETHYLENE ETHER DIOL CONTAINING COATING COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-10-07 WO claimed
US-20040185263-A1 Coating composition containing polytrimethylene ether diol useful as a primer composition AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2004-09-23 US claimed
US-4107256-A SILICONE SURFACTANT, PREPOLYMERS, CURING THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-08-15 US claimed