Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516907 | 0.81 | KDM4E (0.46) | CA2CA12CA1CA9CA14 | |
| SCHEMBL29492895 | 0.81 | KDM4E (0.46) | CA2CA12CA1CA9CA14 | |
| SCHEMBL12301378 | 0.80 | KMT2A (0.44) | CYP2C9CYP2C19NPSR1 | |
| SCHEMBL28855354 | 0.79 | CA12 (0.50) | CA2CA12CA1CA9CA14 | |
| SCHEMBL25143250 | 0.78 | EGFR (0.48) | CA2CA12CA1CA9CA14 | |
| SCHEMBL16138865 | 0.78 | GABRA1 (0.46) | CA2CA12CA1CA9CA14 | |
| SCHEMBL12458913 | 0.78 | EGFR (0.39) | CA2CA12CA1CA9CA14 | |
| SCHEMBL519765 | 0.78 | CA2 (0.50) | TRPV1CA2CA12CA1CA9 | |
| SCHEMBL14785529 | 0.77 | MYC (0.44) | CA2CA12CA1CA9CA14 | |
| SCHEMBL14966330 | 0.77 | GABRA1 (0.44) | CA2CA12CA1CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-9714228-B2 | Dihydrofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-25 | — | — | US | disclosed |
| US-9714228-B2 | Dihydrofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-25 | — | — | US | disclosed |
| EP-2539330-B1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-09 | — | — | EP | disclosed |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-20 | — | — | US | disclosed |
| WO-2013026724-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| US-20120329769-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329769-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2412697-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID COMPOUND | Japan Tobacco, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| WO-2011101229-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
| US-20100286416-A1 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND | JAPAN TOBACCO INC. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286416-A1 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND | JAPAN TOBACCO INC. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286416-A1 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND | JAPAN TOBACCO INC. (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329769-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | FOXM1, NDUFC1, H1-0 | TRPV1 330/4885CA2 257/4885CA12 3157/4885 |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | NQO2, NIT2, QDPR | TRPV1 800/4885CA2 397/4885CA12 2888/4885 |
| US-20100286416-A1 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND | COASY, PCCA, MCCC2 | TRPV1 2568/4885CA2 94/4885CA12 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.