SCHEMBL483218

SCHEMBL483218

c1ccc(-c2cccc3c2oc2ccccc23)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
KDM4E B2RXH2 6/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
ALDH1A1 P00352 4/20 0.45
NPC1 O15118 4/20 0.45
TP53 P04637 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP1A2 P05177 2/20 0.45
RAB9A P51151 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPT P10636 3/20 0.44
MAPK1 P28482 2/20 0.44
JAK2 O60674 1/20 0.43
JAK1 P23458 1/20 0.43
TYK2 P29597 1/20 0.43
JAK3 P52333 1/20 0.43
LMNA P02545 3/20 0.43
CCR1 P32246 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496934 1.00 ALOX5 (0.50) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL483866 0.98 ALOX5 (0.49) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL30531494 0.98 ALOX5 (0.49) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL24793680 0.89 MAOA (0.53) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL24523701 0.89 KDM4E (0.50) KDM4ESMN1; SMN2ALDH1A1NPC1TP53
SCHEMBL24621709 0.89 ALOX5 (0.47) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL15696745 0.87 KDM4E (0.40) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL15672992 0.87 KDM4E (0.41) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL24523663 0.87 ALOX5 (0.48) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1
SCHEMBL26301593 0.86 ALOX5 (0.43) ALOX5KDM4ESMN1; SMN2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
US-12545698-B2 Dinuclear platinum (II) red emitters for OLED applications VERSITECH LIMITED (CN) 2026-02-10 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-12378468-B2 Organometallic compound, organic light-emitting device including the same and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-08-05 US disclosed
US-12310229-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-05-20 US disclosed
US-20240324441-A1 DINUCLEAR PLATINUM (II) RED EMITTERS FOR OLED APPLICATIONS VERSITECH LIMITED (CN) 2024-09-26 US disclosed
US-12069940-B2 Organometallic compound, organic light-emitting device including the same and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-08-20 US disclosed
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-11 US disclosed
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-11 US disclosed
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 US disclosed
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 US disclosed
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 US disclosed
WO-2012158851-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 WO disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378468-B2 Organometallic compound, organic light-emitting device including the same and electronic apparatus including the organic light-emitting device L1CAM, NOM1, MSL1 ALOX5 2277/4885KDM4E 3473/4885SMN1; SMN2 1784/4885
US-12310229-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device L1CAM, AP1M1, AP2M1 ALOX5 2795/4885KDM4E 3988/4885SMN1; SMN2 1951/4885
US-20240324441-A1 DINUCLEAR PLATINUM (II) RED EMITTERS FOR OLED APPLICATIONS OCIAD2, POF1B, OCIAD1 ALOX5 3534/4885KDM4E 4246/4885SMN1; SMN2 3117/4885
US-12069940-B2 Organometallic compound, organic light-emitting device including the same and electronic apparatus including the organic light-emitting device L1CAM, NOM1, MSL1 ALOX5 2277/4885KDM4E 3473/4885SMN1; SMN2 1784/4885
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY POF1B, OCIAD1, OCIAD2 ALOX5 301/4885KDM4E 2307/4885SMN1; SMN2 2007/4885
US-12545698-B2 Dinuclear platinum (II) red emitters for OLED applications OPRD1, POF1B, OCIAD2 ALOX5 3150/4885KDM4E 4302/4885SMN1; SMN2 3075/4885
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, MSL1, EML4 ALOX5 2420/4885KDM4E 3100/4885SMN1; SMN2 1542/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 ALOX5 680/4885KDM4E 3232/4885SMN1; SMN2 3234/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 ALOX5 3699/4885KDM4E 299/4885SMN1; SMN2 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.