Sugi Predict

Sugi Predict / Compounds / SCHEMBL483866

SCHEMBL483866

SCHEMBL483866

[Ir].c1ccc(-c2cccc3c2oc2ccccc23)nc1.c1ccc(-c2cccc3c2oc2ccccc23)nc1.c1ccc(-c2cccc3c2oc2ccccc23)nc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.49
▸ KDM4E B2RXH2 6/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ NPC1 O15118 4/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ TP53 P04637 3/20 0.47
▸ HPGD P15428 3/20 0.47
▸ HSD17B10 Q99714 3/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ MAPT P10636 3/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ JAK2 O60674 1/20 0.43
▸ JAK1 P23458 1/20 0.43
▸ TYK2 P29597 1/20 0.43
▸ JAK3 P52333 1/20 0.43
▸ LMNA P02545 3/20 0.42
▸ CCR1 P32246 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496934 0.98 ALOX5 (0.50) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL483218 0.98 ALOX5 (0.50) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL30531494 0.97 ALOX5 (0.49) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL24793680 0.88 MAOA (0.53) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL24523701 0.88 KDM4E (0.50) KDM4ESMN1; SMN2NPC1ALDH1A1TP53
SCHEMBL24621709 0.87 ALOX5 (0.47) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL15672992 0.86 KDM4E (0.41) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL15696745 0.86 KDM4E (0.40) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL24523663 0.85 ALOX5 (0.48) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1
SCHEMBL26301593 0.85 ALOX5 (0.43) ALOX5KDM4ESMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-30 — — US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 — — US disclosed
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-11637251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 — — US disclosed
EP-3178831-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2020-04-29 — — EP disclosed
EP-3643721-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2020-04-29 — — EP disclosed
US-20180323383-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-11-08 — — US disclosed
US-10056566-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-08-21 — — US disclosed
EP-3178831-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2017-06-14 — — EP disclosed
EP-2411401-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2016-12-21 — — EP disclosed
US-20140203268-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2014-07-24 — — US disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 — — US disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 — — EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885KDM4E 2475/4885SMN1; SMN2 3339/4885
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885KDM4E 2475/4885SMN1; SMN2 3339/4885
US-11637251-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885KDM4E 2475/4885SMN1; SMN2 3339/4885
US-10056566-B2 Organic electroluminescent materials and devices NR2E3, SOD1, RER1 ALOX5 1680/4885KDM4E 2692/4885SMN1; SMN2 2090/4885
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885KDM4E 2475/4885SMN1; SMN2 3339/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 ALOX5 680/4885KDM4E 3232/4885SMN1; SMN2 3234/4885
US-20180323383-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885KDM4E 2475/4885SMN1; SMN2 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.