Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835948 | 0.94 | CDC25B (0.51) | CDC25BALOX15KMT2AMEN1MAPT | |
| SCHEMBL14269199 | 0.85 | GAA (0.61) | GAAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4826745 | 0.78 | MAPT (0.57) | GAAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL4836070 | 0.74 | LMNA (0.56) | GAAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4830389 | 0.72 | KDM4E (0.63) | CDC25BKMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL4830399 | 0.71 | GAA (0.48) | GAAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28216149 | 0.70 | KMT2A (0.52) | GAACDC25BKMT2AMEN1MAPT | |
| SCHEMBL6312871 | 0.69 | ALDH1A1 (0.56) | CDC25BKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3265630 | 0.68 | MAPT (0.64) | GAACDC25BALOX15KMT2AMEN1 | |
| SCHEMBL859755 | 0.68 | CDC25B (0.52) | CDC25BKMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329651-B2 | Cannabimimetic ligands | UNIVERSITY OF CONNECTICUT (US) | 2008-02-12 | — | — | US | disclosed |
| US-20040077649-A1 | Novel cannabimimetic ligands | CONNECTICUT, UNIVERSITY OF | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077649-A1 | Novel cannabimimetic ligands | CNR2, CNR1, GPR18 | GAA 3345/4885CDC25B 3243/4885ALOX15 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.