Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21121950 | 0.84 | ALDH1A1 (0.51) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL1415937 | 0.82 | EPHX2 (0.51) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL2095021 | 0.79 | GAA (0.53) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL31492474 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL7624194 | 0.79 | CASP1 (0.68) | ALDH1A1CYP2D6CYP2C19LMNACASP1 | |
| SCHEMBL8621389 | 0.77 | GAA (0.55) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL1720194 | 0.77 | ALDH1A1 (0.67) | ALDH1A1CYP2D6CYP2C19GAABCHE | |
| SCHEMBL29665196 | 0.76 | BCHE (0.53) | ALDH1A1CYP2D6CYP2C19LMNAGAA | |
| SCHEMBL1415939 | 0.76 | PLAU (0.52) | ALDH1A1CYP2D6CYP2C19GAABCHE | |
| SCHEMBL23349345 | 0.76 | THRB (0.56) | ALDH1A1CYP2D6CYP2C19LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396650-A | Ink-absorbing coating | 吉安天晟新材料有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-111171210-A | Tetrafluoroethylene-alkenyl carbamate-perfluoroalkyl vinyl ether dispersion resin and microporous membrane prepared therefrom | 苏州世华新材料科技股份有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-112823037-B | Inhibition of deubiquitinase USP25 and USP28 | 瓦洛健康股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-116396650-A | Ink-absorbing coating | 吉安天晟新材料有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-112939815-A | Carbamate containing terminal double bonds, preparation method thereof and polymer | 贵州大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-112823037-A | Inhibition of deubiquitinase USP25 and USP28 | 瓦洛早期发现股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-108440230-B | Preparation method of olefin and method for synthesizing Chondriamidea and ChondriamideC | 中国科学技术大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-111171210-A | Tetrafluoroethylene-alkenyl carbamate-perfluoroalkyl vinyl ether dispersion resin and microporous membrane prepared therefrom | 苏州世华新材料科技股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| US-8604030-B2 | Fused piperidine compound and pharmaceutical containing same | KOWA COMPANY, LTD. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120108581-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL CONTAINING SAME | KOWA COMPANY, LTD (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2412710-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2012-02-01 | — | — | EP | disclosed |
| CN-101616897-A | The ethylamino-phenyl derivatives that heterocyclic radical replaces, its preparation and as the purposes of medicament | ESTEVE LABOR DR | 2009-12-30 | — | — | CN | disclosed |
| US-20090005354-A1 | New Amino Derivatives and Their Use as Pharmaceuticals | PFIZER, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1758862-A1 | AMINOPYRIDINE DERIVATIVES AS SELECTIVE DOPAMINE D3 AGONISTS | Pfizer Limited (GB) | 2007-03-07 | — | — | EP | disclosed |
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
| WO-2005115985-A1 | AMINOPYRIDINE DERIVATIVES AS SELECTIVE DOPAMINE D3 AGONISTS | PFIZER LIMITED (GB) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | DRD2, DRD1, DRD3 | ALDH1A1 792/4885CYP2D6 785/4885CYP2C19 304/4885 |
| US-20120108581-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL CONTAINING SAME | EPOR, JAK2, HBZ | ALDH1A1 360/4885CYP2D6 445/4885CYP2C19 616/4885 |
| US-20090005354-A1 | New Amino Derivatives and Their Use as Pharmaceuticals | DRD2, DRD1, DRD3 | ALDH1A1 1067/4885CYP2D6 823/4885CYP2C19 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.