SCHEMBL4834491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4834228	0.78	SORT1 (0.45)	NOTUMPOLBNPC1RAB9AALDH1A1
	SCHEMBL7316095	0.73	NOTUM (1.00)	NOTUMMAPTMEN1KMT2A
	SCHEMBL44366	0.72	POLB (0.76)	POLBALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL8094050	0.72	POLB (0.76)	POLBALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL8087428	0.72	POLB (0.76)	POLBALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL4833237	0.71	ALDH1A1 (0.49)	POLBNPC1RAB9AALDH1A1MAPT
	SCHEMBL1460734	0.71	MEN1 (0.72)	POLBMAPTSMN1; SMN2KDM4EPTK2
	SCHEMBL4836703	0.69	POLB (0.51)	POLBNPC1RAB9AALDH1A1MAPT
	SCHEMBL15658983	0.69	POLB (0.56)	POLBNPC1RAB9AALDH1A1MAPT
	SCHEMBL4836274	0.69	ALDH1A1 (0.47)	POLBNPC1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.