Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837690 | 0.93 | HTR1A (0.39) | TRPV3CHEK2AURKBTBK1HDAC3 | |
| SCHEMBL4838842 | 0.93 | HTR1A (0.39) | TRPV3CHEK2AURKBTBK1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4844409 | 0.90 | ALDH1A1 (0.46) | CHEK2AURKBTBK1ALDH1A1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4843340 | 0.87 | CHEK2 (0.40) | CHEK2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL4844677 | 0.81 | KDM4E (0.47) | CHEK2AURKBTBK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4846269 | 0.81 | CHEK2 (0.44) | CHEK2AURKBTBK1 | |
| Trifluoroacetic Acid SCHEMBL4840418 | 0.81 | TBK1 (0.39) | CHEK2AURKBTBK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4842116 | 0.80 | CHEK2 (0.53) | CHEK2AURKBTBK1DHODH | |
| Trifluoroacetic Acid SCHEMBL4837229 | 0.80 | KDM4E (0.40) | AURKBTBK1ALDH1A1HDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4843958 | 0.80 | CHEK2 (0.44) | CHEK2AURKBTBK1ALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | TRPV3 1371/4885CHEK2 309/4885AURKB 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.