Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4843340 | 0.93 | CHEK2 (0.40) | ALDH1A1KDM4EKMT2AMEN1CHEK2 | |
| SCHEMBL4844677 | 0.92 | KDM4E (0.47) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| Trifluoroacetic Acid SCHEMBL4837609 | 0.90 | TRPV3 (0.39) | ALDH1A1CHEK2TBK1AURKBHDAC3 | |
| Trifluoroacetic Acid SCHEMBL4840418 | 0.88 | TBK1 (0.39) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| Trifluoroacetic Acid SCHEMBL4839422 | 0.87 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5260412 | 0.86 | CHEK2 (0.41) | ALDH1A1KDM4ECHEK2TBK1HDAC3 | |
| SCHEMBL4834728 | 0.85 | CHEK2 (0.40) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL4834809 | 0.84 | KMT2A (0.44) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4842116 | 0.83 | CHEK2 (0.53) | CHEK2TBK1AURKB | |
| Trifluoroacetic Acid SCHEMBL4837229 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4EKMT2AMEN1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ALDH1A1 1489/4885KDM4E 2903/4885KMT2A 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.