Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843534 | 0.76 | CA12 (0.47) | CA12CA4CA7CA9CA14 | |
| SCHEMBL5035892 | 0.71 | GABRA1 (0.48) | ALDH1A1 | |
| SCHEMBL1981756 | 0.69 | ERN1 (0.41) | — | |
| SCHEMBL27157043 | 0.67 | ERN1 (0.44) | — | |
| SCHEMBL25419672 | 0.67 | TSHR (0.43) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL5987657 | 0.66 | MTNR1A (0.58) | KDM4EF13A1MTNR1AMTNR1BBLM | |
| SCHEMBL28775677 | 0.65 | GABRA1 (0.45) | — | |
| SCHEMBL8535693 | 0.64 | KDM4E (0.59) | CA12CA4CA7CA9CA14 | |
| SCHEMBL28968695 | 0.64 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL5988147 | 0.64 | MTNR1A (0.57) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449315-B2 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070167644-A1 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE, INC. (US) | 2007-07-19 | — | — | US | disclosed |
| EP-1392204-A4 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE INC (US) | 2007-07-18 | — | — | EP | disclosed |
| US-7157458-B2 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060106204-A1 | Bifunctional energy-reversible acyl-compositions | GILBERT CARL W | 2006-05-18 | — | — | US | disclosed |
| EP-1392204-A2 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CryoLife, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20020187993-A1 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. | 2002-12-12 | — | — | US | disclosed |
| WO-2002083030-A2 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187993-A1 | Bifunctional energy-reversible acyl-compositions | ACACB, ACACA, ACAT1 | CA12 739/4885CA4 1121/4885CA7 1034/4885 |
| US-20070167644-A1 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | ACACB, ACAT1, ACACA | CA12 729/4885CA4 1132/4885CA7 1045/4885 |
| US-20060106204-A1 | Bifunctional energy-reversible acyl-compositions | ACACB, ACAT1, ACACA | CA12 729/4885CA4 1132/4885CA7 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.