SCHEMBL4840342

SCHEMBL4840342

C=Cc1ccccc1C[PH](CCCCCCCCCCCC)(CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
LIPG Q9Y5X9 1/20 0.36
ALDH1A1 P00352 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4835886 1.00 THRA (0.37) THRATHRBLIPGALDH1A1NR1H2
SCHEMBL2346267 1.00 THRA (0.37) THRATHRBLIPGALDH1A1NR1H2
SCHEMBL2344700 0.94 ALDH1A1 (0.33) THRATHRBLIPGALDH1A1
Phosphine SCHEMBL8143769 0.92 ALDH1A1 (0.32) THRATHRBLIPGALDH1A1
SCHEMBL8669532 0.81 LIPG (0.43) THRATHRBLIPGALDH1A1NR1H2
SCHEMBL20567945 0.81 ALDH1A1 (0.33) ALDH1A1
SCHEMBL8019676 0.80 ALDH1A1 (0.38) ALDH1A1
SCHEMBL465113 0.78 LIPG (0.53) THRATHRBLIPGNR1H2NR1H3
SCHEMBL9488801 0.78 LIPG (0.53) THRATHRBLIPGNR1H2NR1H3
SCHEMBL10625167 0.78 LIPG (0.53) THRATHRBLIPGNR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7343984-B2 Core sample collector equipped with sterilizing agent-applying mechanism and method of taking core sample INDEPENDENT ADMINISTRATIVE INSTITUTION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) 2008-03-18 US disclosed
US-7308951-B2 Method of coring a crustal core sample and flow-able coating material for coring a crustal core sample INDEPENDENT ADMINISTRATIVE INSTITUTION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) 2007-12-18 US disclosed
US-20050183886-A1 Method of coring a crustal core sample and flow-able coating material for coring a crustal core sample INDEPENDENT ADMINISTRATIVE INSTITUTION JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) 2005-08-25 US disclosed
US-20050106751-A1 Piston corer comprising bactericidal agents for use in isolating subsurface microorganisms JAPAN MARINE SCIENCE & TECHNOLOGY CENTER (JP) 2005-05-19 US disclosed
US-6695076-B2 Method of coring crustal core sample, and antimicrobial polymeric gel and gel material used in the method JAPAN MARINE SCIENCE & TECHNOLOGY CENTER (JP) 2004-02-24 US disclosed
US-20020139583-A1 Method of coring crustal core sample, and antimicrobial polymeric gel and gel material used in the method JAPAN MARINE SCIENCE & TECHNOLOGY CENTER (JP) 2002-10-03 US disclosed