Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835886 | 1.00 | THRA (0.37) | THRATHRBLIPGALDH1A1NR1H2 | |
| SCHEMBL4840342 | 1.00 | THRA (0.37) | THRATHRBLIPGALDH1A1NR1H2 | |
| SCHEMBL2344700 | 0.94 | ALDH1A1 (0.33) | THRATHRBLIPGALDH1A1 | |
| Phosphine SCHEMBL8143769 | 0.92 | ALDH1A1 (0.32) | THRATHRBLIPGALDH1A1 | |
| SCHEMBL8669532 | 0.81 | LIPG (0.43) | THRATHRBLIPGALDH1A1NR1H2 | |
| SCHEMBL20567945 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8019676 | 0.80 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL465113 | 0.78 | LIPG (0.53) | THRATHRBLIPGNR1H2NR1H3 | |
| SCHEMBL9488801 | 0.78 | LIPG (0.53) | THRATHRBLIPGNR1H2NR1H3 | |
| SCHEMBL10625167 | 0.78 | LIPG (0.53) | THRATHRBLIPGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403843-B1 | CHEMILUMINESCENT COMPOSITIONS, METHODS, ASSAYS AND KITS FOR OXIDATIVE ENZYMES | LIFE TECHNOLOGIES CORP (US) | 2018-11-07 | — | — | EP | claimed |
| EP-2165197-B1 | REAGENTS, KITS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES BY ENERGY TRANSFER FROM AN ACTIVATED CHEMILUMINESCENT SUBSTRATE TO AN ENERGY ACCEPTOR DYE | LIFE TECHNOLOGIES CORP (US) | 2011-08-31 | — | — | EP | claimed |
| US-6695076-B2 | Method of coring crustal core sample, and antimicrobial polymeric gel and gel material used in the method | JAPAN MARINE SCIENCE & TECHNOLOGY CENTER (JP) | 2004-02-24 | — | — | US | claimed |
| US-6635437-B2 | Useful in methods for producing light and in assays for phosphatase enzymes and enzyme inhibitors and in assays employing enzyme-labeled specific binding pairs | LUMIGEN, INC. | 2003-10-21 | — | — | US | claimed |
| EP-0819119-B1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-20030023089-A1 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes | AKHAVAN-TAFTI HASHEM (US) | 2003-01-30 | — | — | US | claimed |
| US-6296787-B1 | ACRIDINE AND PHENANTHRIDINE ALKENYL PHOSPHATE DERIVATIVES | LUMIGEN, INC. | 2001-10-02 | — | — | US | claimed |
| US-6270695-B1 | HETEROCYCLIC COMPOUNDS WITH EXOCYCLIC DOUBLE BOND HAVING PHOSPHATE GROUP ATTACHED TO DISTAL CARBON; DETECTION SENSITIVITY | LUMIGEN, INC. | 2001-08-07 | — | — | US | claimed |
| US-6218137-B1 | SENSITIVE QUANTITATIVE ANALYSIS USING COMPOUND HAVING A HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND WHICH IS SUBSTITUTED AT DISTAL CARBON WITH PHOSPHATE GROUP AND OXYGEN OR SULFUR GROUP | LUMIGEN, INC. | 2001-04-17 | — | — | US | claimed |
| US-6139782-A | A CHEMILUMINESCENT CONTAINING A HETEROCYCLIC RING GROUP AND AN ENOL PHOSPHATE GROUP WHICH REACT WITH OXYGEN UPON REMOVAL OF PHOSPHATE GROUP WITH A PHOSPHATASE ENZYME TO PRODUCE AN ENOLATE WHICH REACTS WITH TO PRODUCE CHEMILUMINOESCENCE | LUMIGEN, INC. (US) | 2000-10-31 | — | — | US | claimed |
| US-6090571-A | REACTING PHOSPHATASE WITH NITROGEN-CONTAINING HETEROCYCLIC RING SYSTEM HAVING AN ENOL PHOSPHATE GROUP, DETECTING THE CHEMILUMINESCENCE, AND RELATING TO AMOUNT OF ANALYTE | LUMIGEN, INC. (US) | 2000-07-18 | — | — | US | claimed |
| US-6045727-A | NITROGEN CONTAINING HETEROCYCLIC RING SYSTEM BEARING AN EXOCYCLIC CARBON-CARBON DOUBLE BOND. THE DOUBLE BOND IS FURTHER SUBSTITUTED AT THE DISTAL CARBON WITH A PHOSPHATE GROUP AND AN OXYGEN OR SULFUR ATOM-CONTAINING GROUP. | LUMIGEN, INC. (US) | 2000-04-04 | — | — | US | claimed |
| EP-0561033-B1 | Polymeric phoshonium salts providing enhanced chemiluminescence from 1,2-dioxetanes, and their use. | LUMIGEN INC (US) | 2000-03-15 | — | — | EP | claimed |
| EP-0819119-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 1999-04-14 | — | — | EP | claimed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | claimed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | claimed |
| US-7343984-B2 | Core sample collector equipped with sterilizing agent-applying mechanism and method of taking core sample | INDEPENDENT ADMINISTRATIVE INSTITUTION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) | 2008-03-18 | — | — | US | disclosed |
| US-7308951-B2 | Method of coring a crustal core sample and flow-able coating material for coring a crustal core sample | INDEPENDENT ADMINISTRATIVE INSTITUTION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20020139583-A1 | Method of coring crustal core sample, and antimicrobial polymeric gel and gel material used in the method | JAPAN MARINE SCIENCE & TECHNOLOGY CENTER (JP) | 2002-10-03 | — | — | US | disclosed |
| EP-0561033-B1 | Polymeric phoshonium salts providing enhanced chemiluminescence from 1,2-dioxetanes, and their use. | LUMIGEN INC (US) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030023089-A1 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes | PPP6C, PPP4C, PPP2CA | THRA 4748/4885THRB 4236/4885LIPG 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.