Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 10/20 | 0.42 |
| ▸ | MMP3 | P08254 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837954 | 0.91 | MCL1 (0.46) | KDM2BMMP8MMP3LMNAMMP1 | |
| Hydrochloric Acid SCHEMBL4840670 | 0.90 | MCL1 (0.45) | KDM2BMMP8MMP3LMNAMMP1 | |
| SCHEMBL4039147 | 0.84 | RORC (0.42) | KDM2BMMP8MMP3LMNAMMP1 | |
| SCHEMBL4034006 | 0.83 | MMP1 (0.40) | KDM2BMMP8MMP3LMNAMMP1 | |
| SCHEMBL4836335 | 0.82 | MMP8 (0.48) | KDM2BMMP8MMP3MCL1 | |
| SCHEMBL4032860 | 0.81 | MAPK1 (0.40) | KDM2BMMP8MMP3LMNAMMP1 | |
| SCHEMBL4842900 | 0.81 | FFAR4 (0.43) | KDM2BMMP8MMP3MMP1MMP2 | |
| SCHEMBL4841693 | 0.80 | FFAR4 (0.43) | KDM2BMMP8MMP3MMP1MMP2 | |
| SCHEMBL4832648 | 0.80 | SCN9A (0.48) | MMP8MMP3LMNAMMP1MMP2 | |
| SCHEMBL4840706 | 0.80 | FFAR4 (0.42) | KDM2BMMP8MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | KDM2B 2971/4885MMP8 3968/4885MMP3 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.