Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617628 | 0.71 | LMNA (0.47) | CTSDLMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL29061582 | 0.67 | MAPT (0.42) | CTSDLMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL10357051 | 0.67 | — | — | |
| SCHEMBL7919790 | 0.65 | MAPT (0.40) | CTSDLMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL4837274 | 0.65 | ACHE (0.47) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4840767 | 0.65 | LMNA (0.40) | CTSDLMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL617504 | 0.63 | CYP3A4 (0.67) | LMNAMAPTALDH1A1CYP2D6MEN1 | |
| SCHEMBL8582109 | 0.61 | LMNA (0.36) | CTSDLMNAMAPTALDH1A1CYP2D6 | |
| Propane SCHEMBL2359635 | 0.61 | CYP3A4 (0.41) | LMNAMAPTTSHRCYP3A4KDM4E | |
| SCHEMBL9728 | 0.58 | MAPT (1.00) | CTSDLMNAMAPTALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378537-B2 | Olefin oligomerization catalysts and methods of using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-05-27 | — | — | US | disclosed |
| US-20080027188-A1 | OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-01-31 | — | — | US | disclosed |