Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617504 | 0.88 | CYP3A4 (0.67) | LMNAMAPTCYP3A4TDP1MEN1 | |
| SCHEMBL9623978 | 0.84 | NPC1 (0.40) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL9624735 | 0.78 | CYP1A2 (0.53) | LMNACYP3A4TDP1MEN1KMT2A | |
| SCHEMBL14422401 | 0.76 | MAPT (0.53) | LMNAMAPTCYP3A4MEN1KMT2A | |
| Pyridine SCHEMBL27493211 | 0.76 | TDP1 (0.67) | LMNAMAPTCYP3A4TDP1MEN1 | |
| Pyridine SCHEMBL9418289 | 0.74 | TDP1 (0.63) | LMNAMAPTCYP3A4TDP1MEN1 | |
| SCHEMBL29061582 | 0.73 | MAPT (0.42) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL10357051 | 0.73 | — | — | |
| SCHEMBL7919790 | 0.71 | MAPT (0.40) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL4840767 | 0.71 | LMNA (0.40) | LMNAMAPTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474177-A2 | NON-INVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING RADIOLABELED LIPOPHILIC SALTS | The John Hopkins University (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003065882-A2 | NON-INVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING RADIOLABELED LIPOPHILIC SALTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-08-14 | — | — | WO | claimed |
| CN-118324848-A | Process for preparing cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11981688-B2 | Methods of preparing cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-11981687-B2 | Methods of preparing cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| EP-4361128-A2 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| EP-3880681-B1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4286387-A2 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-110225904-B | Process for preparing cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230257400-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. | 2023-08-17 | — | — | US | disclosed |
| CN-116554262-A | Process for preparing cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2017015495-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2017-01-26 | — | — | WO | disclosed |
| WO-2017015502-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC (US) | 2017-01-26 | — | — | WO | disclosed |
| WO-2017015496-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2017-01-26 | — | — | WO | disclosed |
| US-20130001472-A1 | THIN FILM AND COMPOUND USED IN THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-03 | — | — | US | disclosed |
| EP-2423192-A1 | METAL COMPLEX HAVING AROMATIC LIGAND THAT CONTAINS NITROGEN ATOM | Sumitomo Chemical Company, Limited (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| EP-1474177-A2 | NON-INVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING RADIOLABELED LIPOPHILIC SALTS | The John Hopkins University (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003065882-A2 | NON-INVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING RADIOLABELED LIPOPHILIC SALTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-1996017856-A1 | SYNTHESIS OF BIDENTATE PHOSPHINES | GRIFFITH UNIVERSITY (AU) | 1996-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981687-B2 | Methods of preparing cytotoxic benzodiazepine derivatives | GABRA3, GABRA5, GABRA6 | LMNA 945/4885MAPT 2658/4885CYP3A4 40/4885 |
| US-11981688-B2 | Methods of preparing cytotoxic benzodiazepine derivatives | GABRA3, GABRA5, GABRA6 | LMNA 945/4885MAPT 2658/4885CYP3A4 40/4885 |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | LMNA 2372/4885MAPT 1381/4885CYP3A4 4299/4885 |
| US-20230257400-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | GABRA3, GABRA5, GABRB3 | LMNA 809/4885MAPT 2722/4885CYP3A4 51/4885 |
| US-20130001472-A1 | THIN FILM AND COMPOUND USED IN THE SAME | NR2E3, NR3C1, NR0B2 | LMNA 2177/4885MAPT 2086/4885CYP3A4 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.