Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627923 | 0.78 | MAPT (0.40) | ALDH1A1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL28133998 | 0.78 | MAPT (0.36) | ALDH1A1KDM4ETDP1MAPK1MAPT | |
| SCHEMBL449614 | 0.78 | TSHR (0.43) | ALDH1A1HSD17B10CYP1A2TSHRTDP1 | |
| SCHEMBL2929976 | 0.77 | CYP1A2 (0.46) | ALDH1A1HSD17B10CYP1A2TSHRTDP1 | |
| SCHEMBL30521955 | 0.77 | L3MBTL1 (0.39) | ALDH1A1HSD17B10TSHRTDP1CTSD | |
| SCHEMBL1922270 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL28133068 | 0.77 | MEN1 (0.43) | ALDH1A1KDM4ETSHRNPSR1MAPT | |
| SCHEMBL28134001 | 0.77 | GRM5 (0.42) | ALDH1A1HSD17B10CYP1A2TSHRTDP1 | |
| SCHEMBL10444136 | 0.76 | TSHR (0.42) | ALDH1A1HSD17B10CYP1A2KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL31017535 | 0.76 | BLM (0.48) | ALDH1A1HSD17B10CYP1A2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177085-A1 | Process for the Synthesis of a CPLA2 Inhibitor | DEHNHARDT CHRISTOPH M | 2008-07-24 | — | — | US | disclosed |
| US-7342119-B2 | Process for the synthesis of a CPLA2 inhibitor | WYETH HOLDINGS CORPORATION | 2008-03-11 | — | — | US | disclosed |
| US-20050070723-A1 | Process for the synthesis of a CPLA2 inhibitor | WYETH HOLDINGS CORPORATION (US) | 2005-03-31 | — | — | US | disclosed |
| US-3954827-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070723-A1 | Process for the synthesis of a CPLA2 inhibitor | PLAA, PLA2G4A, PLA2G12A | ALDH1A1 3682/4885HSD17B10 1535/4885CYP1A2 196/4885 |
| US-20080177085-A1 | Process for the Synthesis of a CPLA2 Inhibitor | PLAA, PLA2G4A, PLA2G12A | ALDH1A1 3682/4885HSD17B10 1535/4885CYP1A2 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.