Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922270 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL4841692 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL28827980 | 0.75 | LMNA (0.38) | TSHRALDH1A1SLC6A2HTR2BMAPT | |
| SCHEMBL2631300 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPK1MAPTLMNAHTT | |
| SCHEMBL28134028 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL10306759 | 0.73 | RAB9A (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL28788853 | 0.73 | CYP1A2 (0.51) | TSHRALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL3150956 | 0.73 | HSD17B10 (0.40) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL2929976 | 0.73 | CYP1A2 (0.46) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL30521955 | 0.73 | L3MBTL1 (0.39) | TSHRALDH1A1TDP1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922893-B1 | MOISTURE-CURING COMPOSITIONS, PROCESSES FOR PRODUCING SAME AND USE OF SAME | EVONIK DEGUSSA GMBH (DE) | 2016-04-06 | — | — | EP | claimed |
| EP-1304345-B1 | Aminoalkylalkoxysiloxan containing mixtures , their preparation process and their use | DEGUSSA (DE) | 2005-12-14 | — | — | EP | claimed |
| EP-0997469-B1 | Aminopropyl-functional siloxane oligomers | DEGUSSA (DE) | 2004-07-14 | — | — | EP | claimed |
| JP-6087798-A | — | — | None | — | — | JP | disclosed |
| EP-4709384-A2 | COMBINATION THERAPY FOR TREATMENT OF CANCER | PMV Pharmaceuticals, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024238404-A2 | COMBINATION THERAPY FOR TREATMENT OF CANCER | PMV PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-110467572-B | Synthetic method of 3-sulfonyl quinoline derivative | 温州大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-113573708-A | Polyvalent derivatives of emoxidine | 阿尔萨泰克公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-108358858-B | Deuterium labeled 1-substituted phenyl-4-substituted aniline methyl-1, 2, 3-triazole derivative and preparation method and application thereof | 上海化工研究院有限公司 | 2020-08-28 | — | — | CN | disclosed |
| US-10597493-B2 | Polyimide precursor composition and method of preparing polyimide molded article | FUJI XEROX CO., LTD. (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20180215873-A1 | POLYIMIDE PRECURSOR COMPOSITION AND METHOD OF PREPARING POLYIMIDE MOLDED ARTICLE | FUJI XEROX CO., LTD. (JP) | 2018-08-02 | — | — | US | disclosed |
| US-20030225106-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-12-04 | — | — | US | disclosed |
| EP-1358184-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | Amgen Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2003072655-A1 | ENCAPSULATING EPOXY RESIN COMPOSITION, AND ELECTRONIC PARTS DEVICE USING THE SAME | HITACHI CHEMICAL CO., LTD. (JP) | 2003-09-04 | — | — | WO | disclosed |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | disclosed |
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-11-07 | — | — | US | disclosed |
| WO-2002066470-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2002-08-29 | — | — | WO | disclosed |
| JP-H0687798-A | PREPARATION OF NEW PHENYL PROPYNYL AMINE DERIVATIVE | CHINOIN GYOGYSZER V T G RT | 1994-03-29 | — | — | JP | disclosed |
| EP-0006452-B1 | HYPOGLYCEMIC PHENYLPROPYNYLAMINO BENZOIC ACIDS, THEIR SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS AND THEIR APPLICATION | THE DOW CHEMICAL COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| EP-0006452-A1 | Hypoglycemic phenylpropynylamino benzoic acids, their salts, pharmaceutical compositions containing said compounds and their application | THE DOW CHEMICAL COMPANY (US) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | TET2, ALKBH3, FTO | TSHR 4832/4885ALDH1A1 1029/4885TDP1 869/4885 |
| US-20030225106-A1 | Substituted alkylamine derivatives and methods of use | NAT1, PIGO, AADAC | TSHR 2749/4885ALDH1A1 389/4885TDP1 639/4885 |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AADAC, NAT1, PIGO | TSHR 3229/4885ALDH1A1 261/4885TDP1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.