Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835006 | 0.93 | KDM4E (0.44) | ALDH1A1KDM4EGLABRD4USP2 | |
| Trifluoroacetic Acid SCHEMBL4844160 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EGLAMAPTSCN1A | |
| Trifluoroacetic Acid SCHEMBL4840800 | 0.91 | CHEK2 (0.45) | CHEK2TBK1 | |
| Trifluoroacetic Acid SCHEMBL4841832 | 0.90 | NPSR1 (0.39) | ALDH1A1KDM4EMAPTSCN1ASCN5A | |
| Trifluoroacetic Acid SCHEMBL4842213 | 0.89 | POLB (0.48) | KDM4EGLAMAPTCYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL4844675 | 0.87 | HTR7 (0.49) | ALDH1A1MAPTCACNA1GKCNH2LMNA | |
| Trifluoroacetic Acid SCHEMBL4839418 | 0.87 | SCN1A (0.42) | SCN1ASCN5ASCN9AUSP2SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4844696 | 0.86 | CACNA1G (0.56) | KDM4EMAPTCACNA1GKCNH2LMNA | |
| Trifluoroacetic Acid SCHEMBL4842369 | 0.86 | SCN1A (0.41) | SCN1ASCN5ASCN9ACHEK2 | |
| Trifluoroacetic Acid SCHEMBL4841950 | 0.85 | SCN1A (0.44) | SCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ALDH1A1 1489/4885KDM4E 2903/4885GLA 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.