Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838783 | 0.93 | KMT2A (0.43) | CHRNA7DRD4MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4839418 | 0.92 | SCN1A (0.42) | SCN1ASCN5ASCN9ACHRNA7DRD4 | |
| Trifluoroacetic Acid SCHEMBL4841950 | 0.90 | SCN1A (0.44) | SCN1ASCN5ASCN9ACHRNA7 | |
| Trifluoroacetic Acid SCHEMBL4844160 | 0.89 | ALDH1A1 (0.49) | SCN1ASCN5ASCN9AMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4841832 | 0.89 | NPSR1 (0.39) | SCN1ASCN5ASCN9A | |
| Trifluoroacetic Acid SCHEMBL5258099 | 0.88 | TBK1 (0.44) | CHEK2 | |
| Trifluoroacetic Acid SCHEMBL4842213 | 0.87 | POLB (0.48) | CHEK2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4846765 | 0.87 | SCN1A (0.40) | SCN1ASCN5ASCN9ACHRNA7MEN1 | |
| Trifluoroacetic Acid SCHEMBL4841798 | 0.87 | MEN1 (0.53) | SCN1ASCN5ASCN9ACHRNA7CHEK2 | |
| Trifluoroacetic Acid SCHEMBL4844675 | 0.86 | HTR7 (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | SCN1A 1100/4885SCN5A 1762/4885SCN9A 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.